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What is your approach to tapering anesthetic drips for refractory status epilepticus after achieving burst suppression?

1 Answer
Mednet MemberInvited Expert
Neurology · Stanford Health Care Stroke Center
Answered on
  1. Ensure adequate oral/IV ASMs are on board, targeting the receptors appropriately based on the type of status- generalized, focal (e.g., GABA, Na channel, glutamate, etc.). These would include the first, second, and third line as per status protocols. Check levels to ensure adequacy.
  2. At least 24 hours of good seizure/burst suppression (50-70%) on IV anesthetics
  3. Depending on how long the IV anesthetic drips have been used and dose, start walking back in small steps (e.g., 20-25% over X hours, dep...

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