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Topics:
Radiation Oncology • Genitourinary Cancers • Prostate Cancer • Medical Oncology • Nuclear Medicine • ASTRO 2026
Are there any contraindications to Pluvicto therapy you personally use, given that there are none directly provided by the manufacturer?
This question is part of our collaboration with ASTRO to highlight impactful data from the 2026 Multidisciplinary Radiopharmaceutical Symposium. This question is inspired by the Plenary Session Presentation "Clinical Challenges in Radiopharmaceutical Therapy" by Dr. Ana P. Kiess
Answer from: Radiation Oncologist at Academic Institution
In this situation, it is helpful to review the eligibility and exclusion criteria from the VISION protocol directly. These can be found at NCT03511664 (Sartor et al., PMID 34161051). Many of these patients have been heavily pretreated, including prior taxane therapy, so my main concern is that they ...
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Answer from: Radiation Oncologist at Community Practice
I completely agree with Dr. @Anscher's response. Dr. Kendra Harris taught me not to mess with the platelets, so I watch these closely. The Grade 5 events in the VISION trial were bleeding-related.Not strict exclusion criteria but food for thought:PS is important as patients should be able to do IADL...