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Are there any indications on advanced stage Hodgkins disease that one might consider stopping the bleomycin after first two cycles?

Specifically I am thinking if a PET scan shows complete response, would it be reasonable to stop bleomycin and continue AVD?
1 Answer
Mednet Member
Mednet Member
Medical Oncology · Longstreet Clinic Cancer Center
Answered on

The specific question was studied and the results published in NEJM June 2016 Barrington et al- Adapted treatment guided by PETCT in Advanced Hodkins Lymphoma

The results suggested non-inferiority from the standpoint of PFS when bleomycin was omitted after an interim PET/CT suggested no disease. Pati...

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