Are there any special considerations for treatment of metastatic acral melanoma?
Community PollStarted
What is your general treatment approach for metastatic acral melanoma without mutations?
40 physicians have voted
Join Mednetto vote and see how they answered.
2 Answers
Mednet MemberInvited Expert
Medical Oncology · The University Of Chicago Medical Center
Answered on
In general, acral melanoma is a higher-risk disease. There are higher rates of acquired and primary resistance. Given this, I favor ipi-nivo since the overall risk is higher and response rates to single-agent PD-1 or nivo-rela tend to be lower. Emerging data suggest TIL therapy can work reasonably w...
Join for free or sign in to see the full answer
Mednet Member
Medical Oncology · Vanderbilt University
Answered on
I tend to treat these patients aggressively and lean towards ipi/nivo in these patients. Will consider Nivo/Rela if poor performance status.
Join for free or sign in to see the full answer