Are there any successful disease modifying therapy for diffuse idiopathic skeletal hyperostosis (DISH)?
The patient has severe flowing ossification of the anterior and posterior longitudinal ligaments causing nerve compression. HLA B27 negative and SI joints are spared.
2 Answers
Mednet MemberInvited Expert
Rheumatology · Stanford University
Answered on
Therapy for DISH is largely supportive: PT, NSAIDs/pain relievers, and control of contributing metabolic conditions, nutrition, exercise, and lifestyle changes; when necessary surgical interventions such as surgical resection of osteophytes and spinal fusion are required.
Clinical research in DISH is...
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Mednet Member
Rheumatology · University of California (San Francisco) School of Medicine
Answered on
There are no disease modifying agents for DISH and there is no available evidence that controlling the associated metabolic diseases has a disease modifying effect.
Most patients with DISH, in spite of the sometimes exuberant changes on imaging, are asymptomatic. Many patients are diagnosed on the b...
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