Are there certain subsets of ANCA vasculitis patients for whom you would consider life long maintenance therapy?

Overall the field is moving towards longer, and sometimes indefinite maintenance therapy. This is because multiple studies have demonstrated that relapse risk increases when maintenance therapy is stopped. I consider indefinite maintenance therapy for the following patients:

1. Frequent relapsers - ...

The question of whether to provide “lifelong” therapy for some patients with ANCA-associated vasculitis (AAV) addresses what I call a “happy problem” because it arises as a result of both the much higher rate of survival now for patients with AAV compared to only 20 years ago, and reflects that we n...