Are there data to support full-dose anticoagulation added to an antiplatelet in recurrent peripheral arterial thrombosis requiring revascularization and stenting?

Assume the patient does not have another indication for AC like VTE or AFib. Could this be suggestive of a hypercoagulable state?

Community PollStarted

Would you consider adding anticoagulation to antiplatelet therapy for recurrent peripheral artery thrombosis?

76 physicians have voted

Join Mednetto vote and see how they answered.

3 Answers

Mednet Member

Medical Oncology · Los Angeles VA Medical Center

Answered on

This question comes up frequently at our institution. I previously consulted with our vascular surgery team who referred me to this trial of Edoxaban with SAPT, trying to avert what may be limb loss if the bypass graft/stent fails. We've often promoted rivaroxaban 2.5 mg po BID per VOYAGER PAD if we...

Join for free or sign in to see the full answer

Mednet MemberInvited Expert

Cardiology · Lifespan Cardiovascular Institute

Answered on

I am not aware of any data for full dose anticoagulation, only lower dose anticoagulation which was the subject of the VOYAGER PAD study that did show reduced MALE rates when low dose Xarelto was added to either ASA or Plavix.

Join for free or sign in to see the full answer

Mednet Member

Cardiology · USF Health

Answered on

Add the COMPASS Trial to the evidence in support of combined therapy, with an acceptable risk of bleeding.

Join for free or sign in to see the full answer