How would you counsel a woman with a strong family history of thrombosis about oral contraceptives?
Would you recommend avoiding estrogen-containing OCPs?
Would you test for APLS to evaluate for additional thrombotic risk factors? While not hereditary, would a family history of APLS change your decision?
Answer from: at Academic Institution
This can be a complex question for which there are likely no specific data or guidelines upon which to base a recommendation. ASH has published guidelines on thrombophilia testing in VTE (Middeldorp et al., PMID 37195076). They specifically recommend against testing prior to COC prescription. The ra...