Topics:
Breast Cancer • Medical Oncology • NCI-CCC Tumor Board Question • UCLA • Supportive Care • NCI-CCC Breast Tumor Board Question
Are there effective adjunct therapies to relieve tumor flare pain from tamoxifen in the metastatic setting?
Answer from: Medical Oncologist at Community Practice
The current understanding of tamoxifen flare - could be explained by two mechanisms.
One simply induces the necrosis of the tumor by inducing a cytotoxic response. Two, it can actually induce the estrogen mimic phenomenon - which can enhance the metabolism of the tumor itself (or metastatic s...
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