Are there patients who can forgo anticoagulation with asymptomatic, incidentally discovered subsegmental pulmonary embolism?

Of note, there are two ongoing clinical trials that should hopefully provide further data on the definitive management of SSPE (NCT01455818, NCT04263038).

The majority of isolated SSPE are likely not "real" pulmonary emboli but are simply artifacts (Hutchinson et al., PMID 26204274). The ACCP recommends observation for low to intermediate risk patients. These small clots should not cause symptoms, so the misstep that I have seen occur is that too much...