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Are there patients with SLE associated inflammatory arthritis in whom you recommend TNF inhibitors as a treatment option?

Specifically referring to SLE and not a true 'Rhupus' overlap patient. How do you weigh the safety or risk of the use of these agents in SLE patients?
2 Answers
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Rheumatology · UC San Diego
Answered on

In patients who have inflammatory arthritis due to SLE and other causes have been excluded, such as infection, gout, and CPPD, I avoid TNFi therapy due to the concern of flaring lupus disease activity. Alternatively, I tend to add therapy for which there is evidence-based data to support their use, ...

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Rheumatology · UT Southwestern Medical Center
Answered on

I too avoid TNF inhibitors. I will use belimumab, anifrolumab, abatacept, azathioprine, methotrexate or mycophenolate.

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