Are there patients with SLE associated inflammatory arthritis in whom you recommend TNF inhibitors as a treatment option?
Specifically referring to SLE and not a true 'Rhupus' overlap patient. How do you weigh the safety or risk of the use of these agents in SLE patients?
Answer from: at Academic Institution
In patients who have inflammatory arthritis due to SLE and other causes have been excluded, such as infection, gout, and CPPD, I avoid TNFi therapy due to the concern of flaring lupus disease activity. Alternatively, I tend to add therapy for which there is evidence-based data to support their use, ...