Are there situations in which elective nodal volumes may be reduced for T1/T2N0 anal SCC?

I have treated several elderly patients with small tumors using this low dose, limited field regimen. All did well.

There is another paper from France where they looked at the subsequent risk of inguinal nodes in untreated patients. I wish I could remember the reference, but I recall a 14% risk of failure in the nodes.

T1 tumors are not all the same. A well differentiated tumor at the anal verge may not need tr...

I think treatment volume reduction for early anal cancer is worthy of a prospective study. However, there are several caveats. It would be important to have careful imaging to make sure one really is dealing with cN0 disease. I would recommmend FDG PET and careful review of imaging studies, especial...