Are there situations where you would use hypofractionated radiotherapy for Stage III breast cancer?

Would it be acceptable to treat a patient with locally advanced breast cancer (ex pT2N2a) s/p lumpectomy with a short course 4 week treatment instead of conventional 6 weeks, because of patient preference?

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Radiation Oncology · University of Utah

Answered on

The answer to this question is complex, and cannot be adequately explained in a brief response.

Treatment of local advanced breast with hypofractionated radiation is not currently an accepted standard practice in this country. This situation occurs in both breast conservation and mastectomy (+/- reco...

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Radiation Oncology · Cooper Medical School of Rowan University/Cooper University Hospital

Answered on · Updated on

I agree with @Dr. First Last and appreciate his clear and concise review of the literature. In our practice, the only (non-inflammatory) patients for whom we do not offer hypofractionation are those with immediate tissue-expander-based reconstruction. Given the dearth of evidence for such cases, and...

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Radiation Oncology · Varian Medical Systems/Allegheny health network

Answered on

We routinely offer HFRT for PMRT for non inflammatory breast cancer or for patients without immediate reconstruction (we offer them the NRG study). We use 40 Gy in 15 fractions.

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