In patients with hidradenitis suppurativa, are there any specific clinical scenarios where you still hold biologics prior to deroofing or wide local excision for persistent sinus tracts?

I am more concerned about HS flaring with biologic discontinuation than I am about the risks of infection or poor wound healing from the biologic. I cannot think of a scenario where I would hold the biologic for de-roofing or excision.

I haven't found a situation where I would stop a biologic for HS surgery. Before we had data specific to HS, we borrowed from the inflammatory bowel disease literature. There, we saw that continuing biologics through surgery, and for IBD we're talking about bowel resection, was safe and led to bette...