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Are there specific conventional DMARDs and/or biologics that are contraindicated in patients with alpha-gal allergy?

2 Answers
Mednet Member
Mednet Member
Rheumatology · Duke University Medical Center
Answered on · Updated on

Here is a Q&A from AAAAI (American Academy of Allergy, Asthma and Immunology) addressing this question for etanercept and other monoclonal antibodies that are manufactured in cell lines that glycosylate with alpha-gal. The author concludes, "The risk is not zero, but likely very low".

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Mednet Member
Mednet MemberInvited Expert
Allergy & Immunology · Baylor College of Medicine
Answered on

To my knowledge and after review of the literature, no.

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