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Are there specific populations with hypothyroidism for whom you would consider adding liothyronine to levothyroxine therapy, given observational data linking levothyroxine therapy alone to higher risks of dementia and mortality?

Esberard de Lima Beltao, et al., PMID 40579157
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Are there specific populations with hypothyroidism for whom you would consider adding liothyronine to levothyroxine therapy, given observational data linking levothyroxine therapy alone to higher risks of dementia and mortality?

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1 Answer
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Endocrinology · Michigan State University College of Human Medicine
Answered on · Updated on

At this time, there is not enough evidence to routinely add T3 to Levothyroxine for the treatment of Hypothyroidism. Although there is the observational study mentioned above, the authors themselves have stated that further studies are needed to confirm the cognitive and mortality benefits of adding...

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