Are there subgroups of patients with pemphigus in whom you prioritize lower-dose rituximab regimens?
What clinical factors guide this? Age, coborbidities, disease duration, disease severity?
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Do you utilize ultra-low-dose rituximab regimens in your patients with pemphigus?
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2 Answers
Mednet MemberInvited Expert
Dermatology · Duke University
Answered on
No, I do not recommend ultra-low-dose rituximab for my patients. In general, even for patients with comorbidities, the overall complication rate with rituximab infusions is low, with infusion reaction being the most common, and this rarely has any long-term consequences for the patient. In Dr. Werth...
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Mednet Member
Dermatology · University of Pennsylvania
Answered on
Lower doses don’t work as well, with less depletion and earlier relapses.
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