Based upon recently published information in the journal Science, would you offer zileuton to a high-risk food allergy patient who declines oral immunotherapy and omalizumab?

The data suggests that zileuton was not effective in preventing anaphylaxis.

No. This suggestion is based on mice models where one dose eliminated allergic responses to foods like peanuts and eggs. It's moving to phase 1 trials which is encouraging, but we'll have to wait and see how this plays out. On a quick lit search, I did not find any existing case reports of protectio...

I am not aware of any clinical data on this subject. The mouse data is interesting, but many exciting discoveries in mice have failed in human trials.

One would think there would have at least been case reports of food allergic patients, on zileuton for their asthma, who noted they were spared anaph...