Can aplastic anemia present with multiple infiltrative bone lesions, such as in the spine and pelvis?

There are several studies showing diffuse hypointense pictures with an infiltrative-like pattern on MRI in aplastic anemia and MDS. Some aplastic anemia and refractory cytopenia of childhood show patchy pattern of hematopoiesis with some regions having increased fat fraction and some remnants of hem...

It is exceedingly unlikely that such bone lesions are due to aplastic anemia. AA is the absence of hematopoiesis, so there is no mechanism for bone lesions to be present.

I have seen a similar presentation in a child with severe myelosclerosis that appeared as infiltrating bone lesions with pancytopenia, as well as in megakaryocytic leukemia that can present as pancytopenia for a while before abnormal blasts are identified. I am sure that bone marrow biopsy/sometimes...