Can any non-SBRT hypo fractionation regimen for prostate cancer be regarded as the new standard of care, or as an equal alternative standard of care?

RTOG 04-15 (N = 1092) – W Robert Lee et al.

Disease state: Low risk PC

Randomization: 73.8 Gy RT in 1.8 Gy fx’s versus 70 Gy RT in 2.5 Gy fx’s (Non-inferiority design)

Median Follow up: 5.8 years

Toxicity: Significant increases in both Gr 2 + and Gr 3 + late GI and late GU toxicity with hypofraction...

I don't like the term "standard of care" because it is imprecise; it means different things to different people and (especially when preceded by the word "the") implies that there is only one way to do things. There is no agreed upon medical definition, although there is a definition embedded in the...