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Can radiation to the breast be given in the setting of prior radiation for Hodgkin's lymphoma?

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Mednet Member
Mednet Member
Radiation Oncology · Varian Medical Systems/Allegheny health network

Based on previous dose and volume (as most people are getting ISRT and between 20-30 Gy), either whole breast or partial breast RT are usually options. One concern I have is the increase IBTR which is most likely new primary in these patients because of prior RT exposure (akin to BRCA mutation).

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Mednet Member
Mednet Member
Radiation Oncology · Sutter Health N. Cal

I have offered these patients breast conservation with breast TARGIT-IORT with success.

Here are some articles that include Hodgkin's patients who received mantle radiation and later developed a new breast cancer who then received TARGIT-IORT:

Chin et al., PMID 28894694

Thangarajah et al., PMID 293359...

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