Can SBRT be considered for high risk prostate cancer?

There are many ways to address this question:

1. The academic "letter of the law" purist: "If a patient population was included within a clinical trial then the trial results apply to them. Subset analyses are hypothesis-generating."

By this logic: HYPO-RT PC enrolled about 11% high-risk disease and s...

As someone who does actively enroll patients on a trial investigating SBRT for high risk prostate cancer, I do not think there are enough data available to support treating high risk prostate cancer with SBRT outside of a clinical trial. Patients with high risk prostate cancer have multiple, potenti...

I agree 100% with Dr. @Dr. First Last. We shouldn't substitute an investigational option off-trial when we already have multiple effective, safe options. My hope is that SBRT will become a standard for high-risk localized prostate cancer maybe in the near future, but for now we're not there yet, and...