Can you use leflunomide and rituximab in a patient with both multiple sclerosis and rheumatoid arthritis?

It is rare for a patient to have both diseases, but immunosuppressive therapy can be used for the management of both conditions. A study published in 2021 investigated the use of a combination of rituximab and leflunomide in rheumatoid arthritis (Behrens et al., PMID 33738492). Rituximab has previou...

Although teriflunomide is not an immunosuppressant, I always worry about agents, that can alter white count, neutrophil count and lymphocyte count, and the potential risks of infection, not much of an answer, but again I am cautious about dual use with some of the newer therapies