Hematologic Malignancies

Benign Hematology

Questions discussed in this category

Is bone marrow biopsy indicated in patients with primary polycythemia but negative for JAK2 mutation including exon 12?

2 Answers available

Would you give IV iron for low TSAT in patients with MDS anemia who are transfusion independent but on an ESA?

i.e. similar to CKD anemia?

1 Answer available

Would you consider using HMA in management of polycythemia vera?

i.e. treatment-refractory PV, prior to progression to PMF or AML

1 Answer available

What are contraindications for growth factors in patients with hematologic malignancies?

2 Answers available

In the absence of symptoms would you still treat high risk myelofibrosis if transplant ineligible?

Is leukocytosis and thrombocytosis alone an indication for treatment?

1 Answer available

Would you treat iron deficiency in post PV myelofibrosis if anemia is the predominant concern?

1 Answer available

In which patients with oncologic or hematologic disorders are you recommending a 3rd dose of mRNA COVID vaccine?

2 Answers available

What is the role, if any, for next generation sequencing testing in patients with suspected MPN who test negative for commonly identified mutations such as JAK2, CALR, MPL, and BCR-ABL?

3 Answers available

Do you consider splenic response as adequate to judge efficacy of JAK2 inhibitors in myeloproliferative disorders?

1 Answer available

Papers discussed in this category

Blood, 2016-01-21

Whole-exome sequencing identifies novel MPL and JAK2 mutations in triple-negative myeloproliferative neoplasms.

Ann Oncol, 2021 Mar 18

Association of Clinical Factors and Recent Anti-Cancer Therapy with COVID-19 Severity among Patients with Cancer: A Report from the COVID-19 and Cancer Consortium.

Blood Adv, 2020 Dec 22

Erythrocytosis in the general population: clinical characteristics and association with clonal hematopoiesis.

Related Topics in Hematologic Malignancies