Would you give IV iron for low TSAT in patients with MDS anemia who are transfusion independent but on an ESA?

Topics: Hematologic Malignancies • Medical Oncology • Myelodysplastic Syndromes • Anemia • Hematology • Benign Hematology • Iron Homeostasis

i.e. similar to CKD anemia?

Answer from: Medical Oncologist at Academic Institution

Yes. The literature is replete with evidence that iron restricted erythropoiesis mitigates optimal responses to ESAs. It is overwhelmingly likely that an individual receiving erythropoietin or darbepoetin will enjoy longer intervals and dose reduction if the IRE is corrected. I administer a gram of ...

Comments

Medical Oncologist at Alvin & Lois Lapidus Cancer Institute Northwest Hospital
Do you recommend IV iron irrespective of the ferri...

at Kaiser Permanente, Los Angeles Med Center
Please see answer from Dr. @Auerbach to question 1...

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