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Nephrology

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Questions discussed in this category

Would you offer adjuvant immunotherapy in a patient with high risk RCC with new/worsening post-op renal dysfunction and CrCl<30?
KEYNOTE-564 required CrCl 30 or above. Not having a baseline/stable CrCl may make it difficult to diagnose or treat IO nephritis. 
1 Answer available
Do you recommend a kidney biopsy for patients who develop acute kidney injury after starting sacituzumab?
1 Answer available
How do you manage patients blood pressures while on anti-angiogenic TKIs?
Do you insist on ambulatory/home blood pressures to rule in/out white coat hypertension? Does your practice have a system to log patients' BPs to supp...
1 Answer available
What are your management strategies for acute kidney injury attributed to pembrolizumab in patients with a kidney biopsy showing predominately acute tubular injury?
2 Answers available
What are your next steps for managing biopsy-proven interstitial nephritis from checkpoint inhibitors in patients who do not have a response to prednisone?
3 Answers available
Do you recommend preloading with IV magnesium to decrease the risk of cisplatin nephrotoxicity?
3 Answers available
What are your top takeaways from ASN 2023?
2 Answers available
What is your approach to ESA use in patients with ESKD and active malignancy on treatment?
1 Answer available
Do you consider hyperuricemia as a potential etiology of an anion gap metabolic acidosis in patients with elevated uric acid levels and no other readily explainable causes of acidosis?
1 Answer available
Are there preventative measures that you take in your cancer patients with chronic kidney disease who require periodic iodinated contrast CT studies for monitoring of their malignancy?
2 Answers available
Do you recommend a kidney biopsy in a patient with myelodysplastic syndrome diagnosed two years prior who develops new onset proteinuria?
1 Answer available
What factors should prompt a kidney biopsy to evaluate for monoclonal gammopathy of renal significance in a patient with MGUS and suspected chronic diabetic nephropathy?
1 Answer available
How frequently do you monitor urine protein levels in a patient receiving bevacizumab who develops proteinuria of less than 2 grams per day?
2 Answers available
Do you recommend performing a kidney biopsy in patients with suspected ifosfamide nephrotoxicity?
1 Answer available
Would you recommend initiating RRT in a patient with tumor lysis syndrome and a phosphorus of 9 mg/dl or more who does not have symptomatic hypocalcemia or other indications for dialysis?
1 Answer available
Should CAR-T therapy be considered for a kidney transplant patient with refractory PTLD?
1 Answer available
How do you manage hyponatremia in patients with renal cell carcinoma on cabozantinib and nivolumab?
2 Answers available
When do you perform a kidney biopsy in a patient with AKI that is thought to be related to an immune checkpoint inhibitor?
Do you wait to monitor response to empiric corticosteroids before pursuing a kidney biopsy?
2 Answers available
Do you recommend testing for G6PD deficiency in those with whom rasburicase for tumor lysis syndrome is indicated?
2 Answers available
Do you recommend retreatment with an immune checkpoint inhibitor in a patient with a history of immune checkpoint inhibitor-related AKI that resolved with holding the immune checkpoint inhibitor and a glucocorticoid taper?
3 Answers available


Papers discussed in this category

Kidney international reports, 2021 Jan 06
Spectrum of Kidney Involvement in Patients with Myelodysplastic Syndromes.
Cancer, 2017-06-01
Immune checkpoint inhibitors in challenging populations.
N Engl J Med,
Adjuvant Pembrolizumab after Nephrectomy in Renal-Cell Carcinoma.
Cancers, 2022 May 17
Mechanism and Management of Checkpoint Inhibitor-Related Toxicities in Genitourinary Cancers.
International journal of urology : official journal of the Japanese Urological Association, 2023 Jun 06
Tolerability of immune checkpoint inhibitor doublet for advanced renal cell carcinoma patients with pre-dialysis chronic kidney disease or end-stage renal disease.

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