Thoracic Malignancies

Gastrointestinal Cancers   

Questions discussed in this category



For instance, do you factor availability of RNAseq, inclusion of normal blood controls, and QNS rates into your decision?

Please specify how your institution is allocating resources now or will be soon.

I am considering every 6 week pembrolizumab dosing in patients >70 years old in whom I want to reduce clinic visits for, especially in the context ...

Do you offer EPO and TPO support? Do you modify your systemic therapy up front or after subsequent cycles?

For the first treatment day (during combined chemo/XRT courses), is it ok to give XRT first then send the patient for chemo or should the chemo be giv...

As a for instance, a centrally located primary tumor with mediastinal adenopathy that results in a TE fistula? Currently we would recommend esophagea...

What chemotherapy and radiation doses/fractionation would you use once the airway has been stabilized to provide reasonably safe and effective palliat...

Have you ever seen toxicity related to diaphragm dose with conventional fractionation?  

For example, there is a retrospective series out of MD Anderson (Kim, Acta Oncologica 2008) wherein 37 patients with gastric cancer were treated with ...


Papers discussed in this category


J Gastrointest Cancer,

Int. J. Radiat. Oncol. Biol. Phys., 2008 Jan 30

Thorac Surg Clin,

JAMA Netw Open, 2020 Feb 05

Ann Pharmacother, 2021 Jul 20

Ann Transl Med,

Can Fam Physician,

Journal of the National Cancer Institute, 2016-06

Pediatrics, 2014 Feb 02

N. Engl. J. Med.,

The Journal of urology, 2018-12

N. Engl. J. Med.,

Lancet Oncol., 2014 Feb 18

NEJM Evidence, 2022 Jun 1

Br J Cancer, 2014 Apr 15

Cancer, 2011-06-15

Eur J Cancer, 2017 Nov 28

N. Engl. J. Med., 2019 Sep 28

Lancet Oncol, 2021 Jan 18

J Clin Oncol, 2021 Apr 19

J Clin Oncol, 2003 Jul 01

JAMA network open, 2023 Nov 01

The New England journal of medicine, 2023 Jun 04

Nature medicine, 2023 Sep 14

The New England journal of medicine, 2023 Oct 20

Annals of oncology : official journal of the European Society for Medical Oncology, 2023 Oct 05

Lancet (London, England), 2009-10-24

N Engl J Med, 2022 Apr 11

The New England journal of medicine, 2023 Jun 03

The New England journal of medicine, 2023 Oct 21

JTO clinical and research reports, 2023 Aug 16

The New England journal of medicine, 2023 Oct 23

N Engl J Med, 2021 Jun 23

Future oncology (London, England), 2021 Jun 08

Cancer cell, 2021 Jun 17

The New England journal of medicine, 2023 Oct 22

The New England journal of medicine, 2023 Oct 21

Annals of oncology : official journal of the European Society for Medical Oncology, 2023 Oct 11