Cardiology
Expert discussions on heart failure, arrhythmias, interventional procedures, and cardiovascular risk management.
Recent Discussions
Which class(es) of antihypertensives do you recommend for first-line therapy for hypertension in severe aortic stenosis?
Most beneficial data on ACE inhibitors.B blockers are to be avoided if associated AR but prior apparent contradiction is no longer valid and some benefit in outcomes based on their effects. Exact Aortic Stenosis substrate and comorbidities to determine which drugs to benefit. ARB's role is probably ...
Is there a specific INR cut-off value that would prompt you to consider administering vitamin K for patients with mechanical valves requiring urgent non-cardiac surgery and if so, what would be your starting dose?
For urgent surgery that could result in significant bleeding, I would give vitamin K if the INR was 1.6 or higher. I would avoid high doses of vitamin K so as to allow more rapid anticoagulation post-op. Usually one dose of 5mg is enough. I would start low molecular weight heparin post op until INR ...
Is there any difference between colchicine 0.5mg vs 0.6 mg for high risk coronary artery disease?
Based on my subjective practice, no significant difference (have used both formulations). Any others have any different/similar experiences?
Do you think that home INR monitoring is a feasible option for elderly, frail patients with atrial fibrillation on VKA treatment, given variations in socioeconomic status and access to care?
Whenever possible, I prescribe home INR monitoring with appropriate equipment. This allows me to monitor my patients on a weekly basis, rather than on a monthly basis at best. Unfortunately, insurance reimbursement is not standard for this equipment, and many patients are unable to obtain it. The ab...
Would you recommend statin initiation in a young adult patient (age < 40) with type 1 diabetes mellitus and LDL cholesterol levels greater than 100 without any cardiovascular risk factors?
The recommendations are to start statins in young adults with type 1 DM if duration of diabetes is over 20 years.
What is a reasonable surveillance strategy in terms of preferred imaging modality and frequency of monitoring for suspected AV bioprosthetic stenosis in patients status post SAVR?
Echocardiography is the best way to monitor the valve. Obtain baseline images in the first year after implantation. If baseline function is normal and access to care is good, it is not necessary to image every year in the first 5-7 years. The exception to this would be young individuals in whom the ...
Is there any benefit to supervised PAD exercise programs in the presence of collaterals seen on angiography for patients with severe claudication and significant lesions?
Yes, exercise benefits for claudication are more about muscle training and metabolism and general physical conditioning than building of collateral circulation.
Would you favor stopping low-dose aspirin and continuing OAC alone in a patient with atrial fibrillation and mild coronary artery calcification seen on routine chest imaging?
Absolutely, most of the patients that I would treat with dual-antithrombotics (as opposed to dual antiplatelet plus/minus anticoagulant), have had clinical events. Most commonly MI and/ or stent plus atrial fibrillation. Your patient has one clinical event (AF) and another "subclinical" condition.
What is your target or goal lipoprotein (a) level for patients on PCSK9 inhibitors for either primary or secondary prevention?
Let me compliment the clinician who submitted the question because he/she measured lipoprotein (a) [Lp(a)] in the first place. Lp(a) was first described in 1964, but its contribution to atherosclerotic vascular disease risk has only recently attracted widespread attention. Part of that attention is ...
Would you recommend hospitalization for surgery for a large papillary fibroelastoma or atrial myxoma discovered on an outpatient echocardiogram?
NOT necessarily to hospitalize if incidental finding given that both of these lesions are typically present for years prior to diagnosis (unless of course you are concerned about getting sued if a bad outcome occurs). If these lesions are found in the context of a recent neurological syndrome then c...