Cardiology

Do you insist on ambulatory/home blood pressures to rule in/out white coat hypertension? Does your practice have a system to log patients' BPs to supp...

1 Answer available

What is the optimal approach to treat isolated diastolic hypertension?

1 Answer available

Do you recommend increasing dietary potassium intake for blood pressure management in non-CKD patients with hypertension?

1 Answer available

Would you recommend delaying left heart catheterization until development of ESKD in a patient with CKD Stage 5 and stable coronary artery disease given concern for contrast-induced nephropathy?

3 Answers available

When would you consider initiating GDMT for new onset HF in the geriatric population?

1 Answer available

Is there any benefit in maintaining statin or aspirin therapy in patients >75 years old with stable, multivessel ischemic heart disease in light of challenges encountered with polypharmacy?

2 Answers available

In what clinical scenarios do you utilize post-cardiac arrest targeted temperature management (TTM)?

In the span between the HACA trial and the Targeted Temperature Management in Out-of-Hospital Cardiac Arrest study (Dankiewicz et al., PMID 34133859),...

1 Answer available

What is the best approach for single vessel mid-LAD CTO in patient with preserved EF and no anginal symptoms?

7 Answers available

How will you decide between using paclitaxel-coated balloons versus conventional uncoated balloons for managing in-stent restenosis?

1 Answer available

For patients who have undergone ablation for atrial fibrillation with elevated bleeding risk, what is your risk/benefit approach when deciding to continue oral anticoagulation long-term?

1 Answer available

How do you view the balance between opting for percutaneous coronary intervention and prioritizing optimal medical therapy as the initial treatment choice for patients with stable angina?

ORBITA-2 Trial

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What are some device parameters and clinical scenarios in which recommendations should be made to deactivate the LV lead in patients with an existing CRT-D device following LVAD implantation?

1 Answer available

What is your standard approach (i.e. choice of medication, type of sheath) in the cath lab to reduce the likelihood of radial artery spasm?

5 Answers available

When would you consider offering PVC ablation for otherwise healthy patients with preserved LV systolic function?

If PVC burden exceeded 10-15%, would you offer ablation in the absence of specific symptoms?

1 Answer available

Is there a specific INR cut-off value that would prompt you to consider administering vitamin K for patients with mechanical valves requiring urgent non-cardiac surgery and if so, what would be your starting dose?

1 Answer available

How long would you treat a patient with recent history of TAVR presenting with E faecalis bacteremia with unclear source with TEE showing thickened valves but no obvious vegetation?

1 Answer available

Would you recommend hospitalization for surgery for a large papillary fibroelastoma or atrial myxoma discovered on an outpatient echocardiogram?

Would the context of prior stroke/TIA impact the decision to hospitalize or pursue expedited outpatient evaluation?

1 Answer available

How do you decide between ordering coronary calcium scoring versus coronary CTA in asymptomatic patients with low to moderate risk for CAD?

5 Answers available

How do you manage severe hypertriglyceridemia in the adolescent & young adult population receiving chemotherapy for ALL, in the absence of complications related to hypertriglyceridemia?

1 Answer available

What is your preferred anticoagulation/antiplatelet regimen for younger patients presenting with ACS, found to have an acute thrombotic event requiring aspiration thrombectomy without need for stent deployment?

1 Answer available

What are alternate approaches to medical therapy and/or interventions to consider in patients with refractory, severe coronary vasospasm despite short-acting nitrates, calcium channel blockers, L-arginine, and clonidine?

4 Answers available

In light of the NOAH-AFNET6 and ARTESiA trials, how would you approach the decision regarding anticoagulation for patients with incidentally-detected AF <24 hrs on pacemakers/defibrillators?

How would you balance the stroke risk against the bleeding risk? And how would the AF burden play into your decision- would you treat 6 minutes of AF ...

1 Answer available

For patients presenting with ACS and severe aortic stenosis with critical left main disease, would you consider BAV prior to PCI to the left main?

1 Answer available

Do you favor aspirin or P2Y12 inhibitor monotherapy following completion of 12 months of DAPT post-PCI in patients with elevated bleeding risk?

5 Answers available

Would you consider opting for beta blocker withdrawal to improve exercise capacity in patients with heart failure with preserved ejection fraction and chronotropic incompetence?

1 Answer available

How would you lead a goals of care discussion in terms of prognosis/survival likelihood for patients with inotropic dependent HFrEF with CRT-D on maximally tolerated GDMT?

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How do you counsel patients on wearable heart monitor devices when they ask about specific products and diagnostic accuracy of these devices available on the market?

1 Answer available

What is your approach to diagnosis and evaluation of nonbacterial thrombotic endocarditis (Libman-Sacks)?

Patient with negative blood cultures, completed 6 weeks of IV antibiotics and vegetation persists. CT imaging without evidence of malignancy. No evide...

3 Answers available

What is your preferred method for subclinical CAD screening prior to initiation of class IA antiarrhythmic drugs for atrial fibrillation?

1 Answer available

How would you manage a patient with CML in chronic phase with a significant cardiac history, such as heart failure with reduced ejection fraction or arrhythmia?

Is there a specific tyrosine kinase inhibitor that you would prefer to use?

1 Answer available

Would you consider switching choice of P2Y12 inhibitor for patients with ISR (non-ACS presentation), with acceptable bleeding risk?

1 Answer available

Would you initiate anti-arrhythmic drug therapy in patients who are asymptomatic and have normal LV function but with a PVC burden > 20 percent?

2 Answers available

What is your preferred mechanism for venting the left ventricle in patients on VA-ECMO?

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What is a reasonable hemoglobin goal for patients with chronic anemia presenting with acute MI?

1 Answer available

How do you risk stratify patients with different WHO groups of pulmonary hypertension prior to non-cardiac surgeries?

And who would you not recommend to undergo surgeries?

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What would be your second pressor of choice if patients with LVOT obstruction remain persistently hypotensive on phenylephrine?

1 Answer available

Would you favor PCI or CABG for younger patients with radiation-associated cardiac disease in the absence of any significant valvular abnormalities?

For radiation oncologists, how do you ameliorate the risk for radiation-related injury to epicardial coronaries during treatment sessions?

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How do you decide when to refer patients with obstructive hypertrophic cardiomyopathy for alcohol septal ablation versus septal myectomy?

1 Answer available

How do you approach a patient at intermediate ASCVD risk who has been referred to you because of an abnormal coronary CTA (obstructive lesion ~90%) but an excellent exercise capacity on treadmill without angina and a negative MPI?

Had you seen the patient immediately after the coronary CTA results, would you have directly proceeded with cath or also ordered an noninvasive functi...

2 Answers available

Should colchicine be considered in patients with ischemic heart disease and persistently elevated hsCRP despite statin and aspirin therapy and appropriate physical activity?

0 Answers available

What is your approach to secondary stroke prevention in patients with atrial fibrillation and intracranial stenosis (>70%)?

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Given that there are a fair number of myocarditis cases without a troponin elevation, how do you clinically approach the diagnosis of myocarditis?

1 Answer available

When would you consider using hypertonic saline for patients with refractory acute decompensated heart failure and diuretic resistance?

1 Answer available

Can sotalol initiation for atrial fibrillation be performed safely outpatient, and if so, what would be a reasonable protocol for implementing this?

Can sotalol initiation for atrial fibrillation be performed safely outpatient, and if so, what would be a reasonable approach to accomplishing this?&n...

1 Answer available

What would be your threshold to offer coronary angiography for patients presenting with atypical chest pain features and Wellens syndrome on EKG without a troponin elevation or dynamic EKG changes?

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Can CAR T cell therapy be considered for heart transplant recipients with concurrent lymphoproliferative disorders?

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What is your typical approach to the use of beta blockers in the setting of recent cocaine use amongst patients presenting with cocaine-related MI, arrhythmias, or new-onset heart failure?

If these patients were already prescribed non-selective beta blockers outpatient, do you recommend withholding these medications in the acute phase?&n...

1 Answer available

What is your preferred monotherapy antiplatelet agent to continue after completion of DAPT post-PCI for patients with stable ischemic heart disease?

Would coronary disease anatomy influence your selection of which type of antiplatelet agent to continue?

5 Answers available

Are there standardized, discrete cut-off values in T1/T2 mapping and extracellular volume fraction to aid in the diagnosis of various cardiomyopathies, or are these values largely scanner/institution specific?

Is there a role in regional analyses with T1/T2 mapping, such as in the case of RV cardiomyopathies?

1 Answer available

How do you approach treatment planning for lung SBRT in a patient with a lesion within 1 cm of a defibrillator?

The patient is not pacemaker dependent.

5 Answers available

What is your preferred choice of anticoagulant (VKA vs. DOAC) in patients with an LV thrombus and apical infarct?

Would you extend length of time for anticoagulation if the apex remained akinetic on surveillance TTEs?

2 Answers available

Should systemic anticoagulation be considered for patients with a less than 1% atrial fibrillation burden on outpatient monitoring with an elevated CHADSVASc score and acceptable bleeding risk?

1 Answer available

Is there enough evidence now to use injectable semaglutide as a foundational therapy for symptomatic heart failure with preserved ejection fraction in the setting of overweight or obesity?

1 Answer available

Would you recommend that hematologists test for clonal hematopoiesis of indeterminate potential (CHIP) in patients with an intermediate 10-year risk of ASCVD?

Is the data compelling enough to merit intensifying or initiating primary prevention if the patient has CHIP?

1 Answer available

Should we begin using bromocriptine for CVD management during pregnancy per ESC guidelines in patients with peripartum cardiomyopathy?

1 Answer available

Do you routinely use vasopressin in the management of RV failure leading to shock state in the absence of an obvious treatable cause such as infarction or PE?

2 Answers available

In patients presenting with ACS and multivessel disease, when do you favor immediate versus delayed complete revascularization?

If delayed complete revascularization is favored, would you consider staged PCI during that same admission or PCI outpatient?

3 Answers available

Which class(es) of antihypertensives do you recommend for first-line therapy for hypertension in severe aortic stenosis?

1 Answer available

What is a reasonable length of time for systemic anticoagulation in patients presenting with MI in the setting of coronary artery aneurysm with large thrombus formation?

5 Answers available

What is the preferred imaging modality to evaluate subaortic membranes in patients with aortic valve disease?

1 Answer available

Among patients with recovered LVEF on GDMT with a reversible cause for heart failure (i.e., tachycardia-mediated or alcohol-mediated cardiomyopathy), would you consider de-escalation of GDMT?

1 Answer available

Based on results from the VOYAGER PAD trial, when would you consider the primary use of rivaroxaban with aspirin +/- clopidogrel as opposed to conventional aspirin +/- clopidogrel in patients undergoing lower extremity revascularization?

1 Answer available

When would you consider CT aortic valve calcium score over TEE to further delineate the severity of LFLG aortic stenosis?

1 Answer available

How reliable is an exercise stress echo in the diagnosis of exercise-induced heart failure with preserved ejection fraction?

Do you have a specific protocol you follow during the stress echo, and if so, what echo parameters are you using to evaluate for exercised-induced hea...

1 Answer available

Is monitoring for fetal heart block recommended in pregnant patients with only slightly elevated SSA?

2 Answers available

What are the current clinical practices for TEE to guide cardioversion and anticoagulation duration post-cardioversion for Afib/flutter in patients following left atrial appendage closure?

4 Answers available

How do you decide on an outpatient maintenance diuretic regimen for patients approaching discharge for ADHF?

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How frequently should outpatient mobile cardiac telemetry be ordered following resolution of post-CABG-related atrial fibrillation for patients off anticoagulation?

1 Answer available

Should intervention be considered for an intermediate flow-limiting coronary lesion that does not correlate with perfusion defects on stress testing in a patient with atypical anginal symptoms?

7 Answers available

What is your approach to considering geriatric patients for complex PCI given their overall frailty and increased risk of complications such as bleeding and stroke?

2 Answers available

In what situations/patient population would you consider placing an implantable cardiac monitor in favor of external monitors for long-term dynamic monitoring of atrial fibrillation?

What are the real-life implications of the MONITOR-AF study to the routine management of AF?

1 Answer available

What is your approach to monitoring patients with cardiac sarcoid while tapering immunosuppression?

Do you obtain serial cardiac PET scans?

1 Answer available

When would be the appropriate time to refer an asymptomatic young adult with unicuspid AV s/p valvuloplasty during adolescence for AVR following exercise stress TTE findings demonstrating increase in aortic valve mean gradient from 40mmHg to 70mmHg (achieving 15 METS)?

2 Answers available

Are there any indications to close a PFO during pregnancy if a woman had a cryptogenic stroke in her first trimester?

1 Answer available

Would you change an elderly, frail patient with atrial fibrillation who is already on a NOAC to VKA treatment?

In FRAIL-AF, switching VKA therapy to a NOAC was associated with higher risk of bleeding in elderly, frail patients.

4 Answers available

What is your loading dose goal and typical loading regimen for PO amiodarone in patients with atrial fibrillation?

Do you include the amount of IV amiodarone already administered as part of the loading dose?

4 Answers available

Is there a particular PVC/NSVT burden on inpatient telemetry in which you would consider discharging a patient with a LifeVest post-STEMI with newly reduced LVEF <35% while optimizing GDMT?

1 Answer available

How do you calculate QTc intervals in patients being admitted for AAD drug loading who remain in atrial fibrillation or atrial flutter?

1 Answer available

What is your preferred, first-line class of anti-anginals for MINOCA with proven epicardial coronary vasospasm?

1 Answer available

With the recent trials such as SELECT and STEP-HFpEF demonstrating benefits of GLP1-agonists in terms of CV risk reduction and improved exercise function, have you begun to incorporate this class of medications into routine CV health maintenance for patients with HFpEF and/or pre-existing CAD?

2 Answers available

What are your outpatient surveillance strategies (biomarkers, imaging, symptoms) to monitor response to treatment for ATTR amyloidosis with cardiac involvement?

How do you determine duration of therapy for Tafamidis, or is it continued indefinitely for the patient?

1 Answer available

What are your top takeaways from AHA 2023?

4 Answers available

When would you consider initiation of low-dose aspirin for primary prevention and/or statin therapy in patients with acceptable bleeding risk and evidence of coronary artery calcification on prior CT chest imaging?

1 Answer available

What is your approach to counseling an octogenarian on the risks and benefits of LHC in the context of NSTEMI complicated by new-onset heart failure and AKI on CKD?

If LHC is deferred, would you consider loading with plavix and treating for ACS for 48 hours (assuming acceptable bleeding risk) and optimizing GDMT p...

1 Answer available

For patients with high-risk stress test features with ischemic EKG changes and mild to no symptoms, what would be your threshold to directly admit them for coronary angiography, or pursue outpatient elective coronary angiogram?

1 Answer available

Would you start ASA and/or statin therapy on an asymptomatic patient noted to have incidental pathologic Q waves on EKG, assuming no prior history of ischemic heart disease?

Would you consider further imaging like coronary calcium scoring or coronary CTA to further risk stratify them?

1 Answer available

How would you approach the management of a patient with a new diagnosis of cardiomyopathy in pregnancy without clinical signs of heart failure?

4 Answers available

In patients who are on 3 of the 4 pillars of HF therapy for HFrEF, would you add the 4th pillar if they are no longer in symptomatic HF and LVEF normalizes?

The basis of the question is that HFrEF trials enroll patients who have Class II-IV symptoms. If their LV systolic function recovers and they become a...

3 Answers available

What burden of PVCs/NSVT in an inpatient post-MI cardiomyopathy patient would prompt an EP study-guided ICD implantation prior to discharge?

1 Answer available

What other considerations for hyperlipidemia management would you have for a patient with multiple prior PCIs whose LDL remains above goal on high intensity statin, ezetimibe, and evolocumab (assuming compliant with medications)?

2 Answers available

What would be your approach to a patient with new diagnosis of seropositive rheumatoid arthritis manifesting as a constrictive pericarditis with no joint pain complaints?

Would you begin with DMARD therapy like MTX or would you consider starting with an IL-1 antagonist such as Acralyst?

1 Answer available

Do you recommend continuing SGLT2 inhibitors in patients with diabetic kidney disease and congestive heart failure who have been taking the medication for several years and later develop end stage kidney disease?

3 Answers available

Do you think that home INR monitoring is a feasible option for elderly, frail patients with atrial fibrillation on VKA treatment, given variations in socioeconomic status and access to care?

2 Answers available

Do you consider bleeding risk in elderly, frail patients with atrial fibrillation to be similar for all NOACs?

In FRAIL-AF, participants were switched from VKA to dabigatran, rivaroxaban, apixaban, and edoxaban.

2 Answers available

Given recent trials for the management of atrial fibrillation with an early ablation strategy (for example, EAST-AFNET 4, EARLY-AF, PROGRESSIVE-AF, STOP-AF), what is your approach to determining the appropriate timing for ablation in patients with atrial fibrillation?

And how do patient characteristics affect your decisions?

5 Answers available

When would you consider using acetazolamide to augment diuresis in patients with ADHF?

1 Answer available

What is a reasonable amount of ventricular arrhythmia burden on outpatient remote monitoring that would prompt consideration for VT ablation in patients with normal LV function and mild symptoms?

1 Answer available

Should bare metal stents be favored over drug eluting stents for pregnant patients presenting with acute coronary syndrome?

1 Answer available

Do you usually recommend PFO closure for patients with frequent migraines with aura?

1 Answer available

In what clinical context would you consider offering first time catheter ablation for symptomatic atrial fibrillation in patients with advanced heart failure, as opposed to a trial of antiarrhythmics and/or cardioversion?

2 Answers available

Do you recommend checking urine sodium 2 hours after loop diuretic administration to determine the need for dose adjustment in a patient with acute decompensated heart failure?

1 Answer available

What is a reasonable surveillance strategy and length of time to maintain patients with thrombosed bioprosthetic valves on systemic anticoagulation?

1 Answer available

What is your approach to a patient who has a cardiac PET scan suggestive of sarcoid but no other supporting evidence of a diagnosis of sarcoid?

Do you typically push for myocardial biopsy in this case?

1 Answer available

How often and when do you consider trending NT-proBNP levels for patients with HFrEF admitted for acute decompensated heart failure?

1 Answer available

When would you consider proceeding with antiarrhythmic drug load concurrently with DCCV as opposed to DCCV alone in patients with new-onset atrial fibrillation?

1 Answer available

What is your preferred method of lesion interrogation for intermediate left main coronary artery stenosis?

1 Answer available

In which situations do you preferentially use an MCOT in lieu of a standard event monitor?

1 Answer available

How can hepatic venous pressure gradients in patients with cirrhosis be used to differentiate between cardiac cirrhosis and portopulmonary hypertension?

In which clinical scenario(s) would you consider checking HVPG?

3 Answers available

Would you start an amiodarone load for new onset atrial fibrillation with RVR intermittently in normal sinus rhythm to further suppress AF recurrence in the acute setting?

2 Answers available

What is your approach to volume resuscitation in patients with obvious septic shock but also with a component of suspected cardiogenic shock?

4 Answers available

What is your approach to maintenance of sotalol in terms of drug monitoring and duration of therapy for outpatients who remain in normal sinus rhythm?

2 Answers available

Should we routinely include geriatric functional assessments to determine candidacy for TAVR?

(ie., assessing gait speed, cognition, physical function, fall history, orthostatic vital signs, etc.)

1 Answer available

Can Droxidopa be used for augmenting orthostatic hypotension treatment in patients who are already on midodrine and/or fludrocortisone?

Is there an approach to tapering the other two medications while uptitrating Droxidopa dosing to reduce the risk of supine hypertension?

1 Answer available

Following completion of antiplatelet monotherapy (i.e. plavix) plus oral anticoagulation in patients with Afib post-PCI, would you favor continuing antiplatelet therapy + OAC, switching from plavix to aspirin and continuing OAC, or stopping antiplatelet therapy and continuing OAC?

1 Answer available

What is your approach to pacemaker lead thromboses in terms of threshold for lead extraction and initiation of systemic anticoagulation?

1 Answer available

What is your outpatient approach to patients with new-onset paroxysmal atrial fibrillation in the setting of acute illness but who are otherwise asymptomatic with normal sinus rhythm post-hospital discharge?

Specifically, what is your approach to outpatient monitoring to assess atrial fibrillation burden for patients with CHADS2Vasc score>2?

2 Answers available

For patients maintained on antiplatelet monotherapy post-DAPT following PCI, what is your recommendation for holding antiplatelet therapy prior to non-cardiac surgery?

Do you ever recommend "bridging" with low-dose aspirin?

1 Answer available

What is a reasonable blood pressure goal for refractory HTN in the geriatric population?

1 Answer available

Do you recommend noninvasive testing or coronary angiography as the initial test for pre-kidney transplant evaluation of an asymptomatic patient older than 50 years of age with ESKD secondary to diabetic nephropathy and no known history of CAD?

1 Answer available

Should all pregnant patients with newly reduced LVEF <45% be referred as soon as possible to advanced heart failure given high risk for maternal morbidity/mortality in setting of suspected peripartum cardiomyopathy?

If PPCM is suspected, what are your targeted hemodynamic goals during the delivery phase?

1 Answer available

What is your approach to correlating stenotic lesions on coronary angiography to magnitude of decline in LV systolic function or cardiomyopathy severity when deciding to intervene or medically manage stable ischemic heart disease as an outpatient?

1 Answer available

What is your approach to postpartum screening and cardiovascular risk assessment in patients with a prior history of preeclampsia?

Recent AHA guidelines state that all women who have had a diagnosis of preeclampsia in a prior pregnancy should receive an evaluation of cardiac risk....

1 Answer available

When would you consider initiation of bempedoic acid for statin intolerant patients (i.e. LDL threshold, comorbidities)?

How would you assess response to bempedoic acid and its safety on outpatient labs, and how frequently would you have labs monitored?

1 Answer available

Would you consider adding an SGLT2 inhibitor to augment diuresis in patients with worsening renal function presenting with acute decompensated heart failure and AKI on CKD?

1 Answer available

Is it reasonable to consider the use of DOACs for LV thrombus management instead of coumadin?

3 Answers available

When should cardiac MRI be obtained alongside standard echocardiography for outpatient monitoring of the progression of chronic aortic regurgitation?

How often should cardiac MRI be ordered in this context?

1 Answer available

For which patients do you prioritize ambulatory blood pressure monitoring over self-measured blood pressure?

1 Answer available

What are high-risk clinical and echocardiographic features in pregnant patients with congenital heart disease?

1 Answer available

Would you consider a primary prevention ICD in a patient with hypertrophic cardiomyopathy and non-sustained ventricular tachycardia, in the absence of any other high risk predictors for sudden cardiac death?

2 Answers available

What is your approach to GDMT uptitration (particularly dosing for ARBs/ARNIs/MRA) if there is further evidence of renal dysfunction, especially in situations with worsening AKI on CKD?

Would a decrease in eGFR by more than 30% prompt you to consider decreasing or discontinuing these medications?

3 Answers available

Should patients of advanced maternal age (>35 years of age) undergo routine cardiovascular risk stratification with echocardiogram during pregnancy?

1 Answer available

What is the appropriate cardiac work-up and management for an otherwise healthy individual who has experienced immersion pulmonary edema while scuba diving?

For the first time in my 27-year career, I was asked to consult on a patient in his early 40s with immersion pulmonary edema from scuba diving. &...

2 Answers available

What is your preferred pharmacologic agent for recurrent VT suppression in arrhythmogenic right ventricular cardiomyopathy?

1 Answer available

What EKG findings are most concerning when screening asymptomatic athletes in the outpatient setting?

4 Answers available

How do you approach mitral valve endocarditis associated with a large vegetation size and severe mitral regurgitation, but without any heart failure, hemodynamic instability or valve destruction?

While the current guidelines favor early surgery (within 48 hrs of diagnosis) for this population based on the results of the EASE trial (link attache...

3 Answers available

When would you consider percutaneous mechanical aspiration of vegetation in right-sided endocarditis?

1 Answer available

What would be the utility of calcium scoring for the evaluation of low-flow low-gradient aortic stenosis, and what cut-off values typically fall within the severe range?

1 Answer available

What is your approach to abbreviated DAPT in post-PCI patients (ACS and non-ACS) with high bleeding risk?

1 Answer available

What strategies do you employ to minimize the risk of cardiovascular collapse when intubating a patient with severe pulmonary hypertension?

Do you favor awake intubation in these cases?

2 Answers available

Should patients with co-existing moderate-severe valvular disease (particularly AS and MS) and malignancy requiring radiation therapy undergo more frequent surveillance surface echocardiograms?

1 Answer available

Can DOACs be a reasonable alternative (instead of VKA) for management of LV thrombus post-MI and what is a reasonable follow-up time for surveillance outpatient imaging and subsequent duration of therapy outpatient?

1 Answer available

What is a reasonable duration of time for dual anti-platelet therapy in patients who have undergone placement of a covered coronary stent?

1 Answer available

Should consideration be taken to defer using PW to calculate aortic valve area if LVOT pulsed wave is greater than 1.7 m/s (aliasing velocity)?

1 Answer available

What are the preferred inotropes/vasopressors agents for cardiogenic shock in situations with and without LVOT obstruction?

Is there literature to support superiority of levophed over dobutamine, or vice versa?

1 Answer available

Should a toe-brachial index be obtained in lieu of resting ABI as an initial screen for PAD in high-risk patients such as those with longstanding diabetes or advanced age with stiffened vessels?

1 Answer available

What is your preferred PO afterload-reducing agent immediately after being weaned off inotropic support in cardiogenic shock?

1 Answer available

Would testing for ATTR cardiac amyloidosis be considered in an older patient with bilateral carpal tunnel surgeries and multiple spinal stenosis surgeries, but no obvious cardiac symptoms?

1 Answer available

What percentage of patients with non-sustained focal atrial tachycardia detected on an outpatient Holter develop paroxysmal atrial fibrillation, and how should we identify and treat patients at the highest risk of progressing to PAF?

2 Answers available

What structural features preclude a transcatheter edge-to-edge repair in a patient with severe symptomatic tricuspid regurgitation?

1 Answer available

When would you consider discharging post-TAVR patients on outpatient mobile cardiac telemetry with baseline right bundle branch block without further signs of conduction abnormalities 24-48 hours after the procedure, given risk of developing later-onset conduction abnormalities?

And if so, what is a reasonable length of time for outpatient cardiac monitoring?

2 Answers available

Do you ever utilize lacosimide in patients with atrial fibrillation?

1 Answer available

Would you recommend giving N-acetylcysteine in addition to holding diuretics in a patient with chronic kidney disease and mild hypervolemia who is planned to have a contrast study?

1 Answer available

For patients on immune checkpoint inhibitors presenting with chest pain, dyspnea, fatigue, and troponin elevation, would you recommend early initiation of high dose steroids for empiric treatment of ICI myocarditis while pursuing workup with coronary angiogram, echocardiogram, and/or cardiac MRI, or wait until alternative etiologies have been ruled out?

2 Answers available

What would be your index of suspicion for AL amyloidosis with cardiac involvement in a patient with MGUS to prompt further imaging (and which modality would be preferred)?

1 Answer available

Which clinical and echocardiographic parameters (i.e. LVEF, AVA) do you use when determining patient candidacy for LV device-assisted percutaneous balloon aortic valvuloplasty in patients with cardiogenic shock and severe AS?

1 Answer available

What are your diagnostic and management approaches beyond statin therapy for hyperlipidemia in young adults with significantly elevated LDL levels in isolation (i.e. reasonable calcium score, normal lipoprotein A levels)?

1 Answer available

What would be a reasonable means of mechanical circulatory support as a bridge to AVR for patients with severe aortic regurgitation complicated by cardiogenic shock?

1 Answer available

What is your approach to risk stratification of asymptomatic patients with pre-excitation syndrome?

2 Answers available

When should we consider using acarbose for postprandial hypotension?

1 Answer available

Should vasodilatory therapies be considered first-line in the management of hypertension in patients with severe aortic regurgitation?

2 Answers available

Which hemodynamic parameters can be used to titrate positive pressure ventilation in preload dependent settings such as RV failure, cardiac tamponade, HOCM or hemodynamically significant PE?

2 Answers available

Is there any role for palliative radiation in the treatment of pericardial metastases?

Assuming the patient is symptomatic and/or has compression of ventricles, what field design and dose-fractionation would you use?

2 Answers available

Do you ever initiate on degarelix and then switch to leuprolide for patients with prostate cancer and cardiac risk factors receiving ADT?

If so, how long are they on degarelix before the switch?

2 Answers available

Is there emerging and compelling enough evidence to maintain patients on P2Y12i monotherapy (in lieu of aspirin) following completion of DAPT?

1 Answer available

How do you approach a patient with atrial fibrillation on apixaban who has a new cardioembolic stroke?

3 Answers available

In patients with Afib on anticoagulation and concurrent intracranial atherosclerotic disease, would you consider adding an anti-platelet to anticoagulation if there are recurrent events that could be related to the ICAD?

1 Answer available

How frequently and when should lipoprotein A levels be monitored?

Are there any significant benefits to lowering moderately elevated lipoprotein A levels?

1 Answer available

Is it sufficient to maintain patients with atrial fibrillation and established PAD on a DOAC or VKA alone, or is there an additional benefit to adding an antiplatelet agent for CVD benefit?

If so, would you prefer a P2Y12i over low-dose aspirin?

1 Answer available

What is your surveillance approach for outpatient monitoring of ICI myocarditis?

(i.e. frequency of serial BNP, troponin, cMRI)

2 Answers available

Given recent studies investigating ICI myocarditis biomarkers such as Temra CD8+ cells, is there now a growing selection of clinical biomarkers, besides BNP and troponin, being measured routinely in ICI myocarditis cases?

2 Answers available

When would you consider tapering glucocorticoids in a patient with ICI-associated myocarditis?

2 Answers available

For patients presenting with spontaneous coronary artery dissection, what other non-cardiac/vascular work-up can be considered to further risk stratify them as a predictor for any future cardiovascular events?

1 Answer available

Is there any contraindication to the use of ezetimibe in patients with a history of statin induced necrotizing myopathy?

2 Answers available

Does the presence and location of cerebral microbleeds affect your decision for antithrombotic treatment in patients with atrial fibrillation?

Do you distinguish between primary and secondary prevention? Wilson et al., PMID 31130428 is helpful, but curious how people apply this data in practi...

3 Answers available

Should we have a lower threshold to consider revascularization of coronary lesions in athletes, compared to non-athletes?

1 Answer available

Is there a validated risk prediction model you favor to risk stratify patients for cardiotoxicity prior to initiation of chemotherapy?

1 Answer available

What radiation dose is a risk for damaging function or active leads from a pacemaker?

If the pacemaker receives no dose, what dose are the leads allowed to receive and still function? Should interrogation(s) be done weekly?Does dose per...

3 Answers available

What is a reasonable approach to monitoring mechanical valve function if systemic anticoagulation needs to be held in the setting of an acute intracranial hemorrhage?

1 Answer available

Do you use tolvaptan for management of hyponatremia related to heart failure given the side effect profile and lack of mortality benefit seen in a previous trial?

The EVEREST Outcome trial (Konstam et al., PMID 17384437)

1 Answer available

When you send for molecular studies for polycythemia vera, what are the mutations that predict increased cardiovascular risk?

How do you use this information in clinical practice?

1 Answer available

When would it be reasonable to consider enhanced external counter-pulsation therapy in patients with refractory angina despite maximally tolerated anti-anginal therapy?

4 Answers available

How do you re-stratify patients with a primary prevention ICD in need of a generator change if their LVEF has improved to >40% and they have not previously required any device therapies?

1 Answer available

Would you give doxorubicin and cisplatin for localized chondroblastic osteosarcoma in a patient with prior childhood anthracycline exposure and resultant cardiomyopathy with EF 50%?

3 Answers available

Which factors favor extended dual antiplatelet therapy beyond one year in ACS patients with low bleeding risk?

1 Answer available

How do you approach radiation therapy for a target volume adjacent to a WATCHMAN atrial appendage closure device?

1 Answer available

How do you manage anticoagulation bridging for outpatient ESKD patients given concerns for bleeding risk with enoxaparin in this population?

Would you bridge with enoxaparin 0.7 mg/kg/day in an ESKD patient, as described in a previous retrospective study (Pon et al., PMID: 24718051)?

1 Answer available

Would you recommend PFO closure in patients >60 years old with presumed paradoxical embolism as their mechanism of stroke?

2 Answers available

Should we refer patients with nonischemic cardiomyopathy without a reversible cause for genetic screening, in the absence of any family history of heart failure or sudden cardiac death?

1 Answer available

What is your approach to screening for complete heart block in an asymptomatic pregnant patient with negative SSA and positive SSB antibodies?

1 Answer available

When is an appropriate time to consider endomyocardial biopsy for non-ischemic cardiomyopathy?

1 Answer available

Should statin initiation be considered in young adult patients with autoimmune disease or chronic inflammatory conditions without an elevated ASCVD risk score given risk of underestimation of underlying CVD?

2 Answers available

Should we routinely incorporate iron studies into admissions for acute decompensated heart failure?

If so, how frequently should we measure iron saturation/ferritin levels post-iron infusion?

1 Answer available

Are there situations where you would start treatment for cardiac amyloid in a patient with amyloid seen on biopsy, but still pending mass spectrometry results?

E.g. in a patient with tenuous cardiac function, would starting treatment several weeks earlier potentially improve outcomes?

1 Answer available

Would you consider starting an ACE inhibitor on a patient without CVD or heart failure prior to initiation of anthracyclines to reduce the overall risk of myocardial toxicity?

2 Answers available

What is a reasonable atrial fibrillation percentage burden that would benefit from systemic anticoagulation for a patient with an elevated CHA₂DS₂-VASc score?

2 Answers available

When should we consider screening patients with systemic sarcoidosis for cardiac involvement using cardiac MRI or PET given their high risk for sudden cardiac death and discrepancies between reported cardiac symptoms (2-5%) and evidence of cardiac inflammation on advanced imaging and autopsy findings (>25% of cases)?

1 Answer available

What are your top takeaways from ACC 2023?

3 Answers available

What is your stepwise approach to initiating GDMT in the inpatient setting for newly diagnosed HFrEF?

1 Answer available

Is there a preferred heart rate range for patients with moderate to severe paravalvular leak post-TAVR?

1 Answer available

For young adults (20-39 years of age) with moderate hypercholesterolemia, should we aim to reduce LDL-C levels by > or equal to 50% and maintain them on long-term statin therapy?

1 Answer available

What is your approach to weaning IABPs?

1 Answer available

When would you consider implantable loop recorders for athletes with nonspecific complaints of palpitations/dizziness, without known history of arrhythmias?

1 Answer available

Would you consider coronary artery calcium scoring or coronary CTA for asymptomatic elite competitive sports athletes undergoing routine screening visits, without a family history significant for coronary artery disease?

1 Answer available

How do you counsel high-risk women with congenital heart disease who are looking to conceive?

1 Answer available

For CLL patients with high-risk cytogenetics on ibrutinib who develop a cardiac event such as an MI, would you continue ibrutinib?

Would you continue ibrutinib even if they are placed on anti-platelet therapy such as clopidogrel or ticagrelor? When do you switch to an altern...

5 Answers available

Among asymptomatic patients with chronic, severe primary MR, can serial global longitudinal strain measurements assist with determining timing for repeat surveillance TEEs and/or facilitate timing for MVR?

1 Answer available

How would you choose between left bundle pacing and CRT-P in a patient with a new high-degree AV block and pre-existing reduced LVEF, who does not otherwise meet the criteria for CRT-D?

(Assuming that the patient would require V-pacing almost all the time)

1 Answer available

Is there utility in obtaining pericardial fluid autoimmune labs such as ANA or RF in patients with recurrent idiopathic pericardial effusions, but no other clinical or serologic evidence of rheumatic disease?

2 Answers available

What is your preferred rate control agent for atrial fibrillation with rapid ventricular rate, and why?

1 Answer available

When should we integrate CT calcium scoring into routine outpatient practice to arbitrate severity of aortic stenosis?

1 Answer available

When would you consider obtaining a cardiac CT in lieu of standard TEE for the detection of a left atrial appendage thrombus in atrial fibrillation?

2 Answers available

Would you empirically elective to anticoagulate patients with a remote (i.e. >10 year) history of paroxysmal atrial fibrillation presenting with newly diagnosed CVA, presumed cardioembolic in etiology, without any documented recurrence of AF?

3 Answers available

What precautions do you take prior to CABG in a patient with sickle cell trait?

Please comment on temperature recommendations and role of exchange transfusion.

1 Answer available

Would you consider using DOACs in a young patient with SLE and Libman-Sacks endocarditis, who is negative for APS?

2 Answers available

How are PA diastolic goals established and individualized to reduce HF readmission risk post-CardioMEMs, recognizing the overall unclear clinical value of outpatient PA sensor monitoring?

2 Answers available

What is your approach to initiating and titrating midodrine for both inpatient and ambulatory settings?

1 Answer available

When is an appropriate time to consider genetic testing for cardiomyopathies for athletes as part of risk stratification for sudden cardiac death, in light of heightened prevalence of cardiac remodeling confounded by exercise and athletic conditioning?

2 Answers available

What are your preferred ventilatory settings/mode(s) for patients with acute hypoxic respiratory failure presenting with severe biventricular dysfunction in cardiogenic shock?

1 Answer available

Which molecular biomarkers do you favor to risk stratify patients (without CV risk factors) before and after undergoing treatment with cardiotoxic cancer treatments?

1 Answer available

Among asymptomatic patients with structurally normal TTE undergoing treatment with anthracyclines or alkylating agents that develop mildly elevated BNP and/or troponin levels, would you consider referring them for cardiac MRI to evaluate for subclinical cardiotoxicity?

1 Answer available

What is your approach to tapering therapy in a patient with recurrent pericarditis now well-controlled on rilonacept?

2 Answers available

Would you favor restarting anticoagulation or pursuing left atrial appendage closure in a patient with hemorrhagic stroke on anticoagulation for non-valvular atrial fibrillation?

3 Answers available

Do you change management in patients that are taking bisphosphonates and develop atrial fibrillation?

1 Answer available

Do you consider the use of bevacizumab in patients with HHT who have high output cardiac failure related to liver AVMs who also have cerebral AVMs?

1 Answer available

At what heart dose would you prospectively refer a patient to cardiology due to anticipated long term risks?

If a patient had prior breast conserving treatment and now has inflammatory breast disease, would you prophylactical send the patient to a cardiologis...

1 Answer available

Would you recommend that a patient with stable coronary artery disease and well-controlled RA on a JAK inhibitor continue on their current therapy?

2 Answers available

When do you start anticoagulation in a patient with cardioembolic CVA secondary to new onset atrial fibrillation with hemorrhagic conversion?

1 Answer available

What are the alternatives to anticoagulation in an individual with an atrial thrombus and absolute contraindications to anticoagulation?

1 Answer available

How does evidence of cerebral amyloid angiopathy/microbleeds affect choices for secondary stroke prevention in patients with a history of ischemic stroke and atrial fibrillation?

How do you approach secondary stroke prevention for patients with ischemic stroke, atrial fibrillation, and signs of cerebral amyloid angiopathy/micro...

1 Answer available

How would you treat an elderly patient with borderline cardiac dysfunction who has stage 3 HR+ HER2- breast cancer?

2 Answers available

Do you start anticoagulation in a patient with infective endocarditis who also has atrial fibrillation and stroke?

1 Answer available

What are your considerations for peri-operative anticoagulation in patients with a mechanical heart valve undergoing a major noncardiac surgery?

Please comment on bridging.

1 Answer available

For patients with atrial fibrillation on DOAC, when should they resume DOAC after a thalamic bleed without intraventricular bleed?

How does presence of intraventricular hemorrhage change your recommendations?

2 Answers available

Do you consider 10MV beams safe in a patient with an implantable cardiac device?

Recent Japanese guidelines recommend <10MV beams, heart rhythm society and AAPM suggest up to 10MV beams are safe, recommending ≤10MV beams. Giv...

1 Answer available

Given the "LDL Paradox", in which RA patients with the highest levels of inflammation can have ultra-low levels of LDL (<70), how do you approach initiation of statin therapy in these patients?

Dr. Charles-Schoeman presented data at ACR 21 showing that, paradoxically, there is a U-shaped relationship between inflammation and LDL levels in pat...

1 Answer available

How do you counsel patients regarding the cardiovascular risk of febuxostat?

1 Answer available

What is your approach to CLL in patients with atrial fibrillation and/or on anticoagulation?

Do you feel comfortable with BTK inhibitors in these patients? In ELEVATE-RR patients on a/c were excluded, and rate of atrial fibrillation in the ac...

3 Answers available

When do you start anticoagulation for secondary prevention in patients with HFrEF and history of embolic strokes?

For a relatively young, medically compliant patient with HFrEF (EF<35%) and h/o embolic stroke, what is the consensus of starting AC for secondary ...

1 Answer available

What criteria do you use on echocardiogram and PFT to determine who needs further evaluation for CTD-associated pulmonary hypertension?

1 Answer available

When is the best time to consider left atrial appendage closure for secondary stroke prevention in patients with atrial fibrillation?

For example, with a Watchman device? What is the evidence behind this?

1 Answer available

When do you restart anticoagulation in patients with atrial fibrillation who just had an ischemic stroke?

1 Answer available

How do you determine the timing of anticoagulation for patients with large MCA strokes secondary to atrial fibrillation?

1 Answer available

For a patient with cardiac sarcoma, is there a minimum ejection fraction to proceed with adjuvant radiation therapy?

1 Answer available

When is it necessary to monitor the QTc interval in patients on hydroxychloroquine?

2 Answers available

Is dexrazoxane recommended for cardioprotection in AYA patients with Hodgkin lymphoma who are receiving anthracyclines as part of their upfront therapy?

3 Answers available

Would you give anthracycline chemotherapy to a patient with HR+, HER2 negative inflammatory breast cancer who has history of cardiomyopathy with LVH and moderately reduced EF but most recent echo shows improvement to normal or near normal ejection fraction?

If no anthracycline, what alternative regimen would you consider?

5 Answers available

Would you modify your initial treatment for a patient with de novo metastatic HR- HER2+ breast CA who has cardiomyopathy at baseline (EF < 35)?

Is there any safety data to proceed with TKIs/TDM-1 or to proceed as standard with THP?

1 Answer available

What steroid sparing agent do you use for treatment of cardiac sarcoidosis?

Does the type of cardiac involvement impact this choice?

2 Answers available

Is it safe to use statins in IIM patients if HMGCR antibodies are negative?

1 Answer available

How do you balance short-course ADT in unfavorable intermediate risk prostate cancer patients with cardiac comorbidities?

1 Answer available

Do you continue hydroxychloroquine in lupus patients who develop cardiomyopathy?

1 Answer available

What is the utility and recommendation for adding troponin and/or BNP to echocardiograms to screen for cardiac dysfunction In breast cancer patients receiving anthracycline based regimens?

1 Answer available

How do you manage calcium and vitamin D supplementation in patients with sarcoidosis on chronic steroids?

1 Answer available

How do you approach the re-challenge with trastuzumab in metastatic HER2+ patients who develop cardiomyopathy on trastuzumab/pertuzumab with subsequent improvement with discontinuation?

Do you repeat the loading dose of trastuzumab?

1 Answer available

What frontline treatment would you offer a patient with AITL who is not a candidate for an anthracycline due to baseline cardiomyopathy?

1 Answer available

Would you recommend cardiac radiotherapy for malignant pericardial effusion refractory to pericardial fenestration?

Would you consider using radiotherapy for persistent malignant pericardial effusion? What dose-fractionation would you use, and what would your ...

1 Answer available

What therapy would you recommend for metastatic myxoid liposarcoma in a young patient with anthracycline cardiomyopathy with EF 25% who failed eribulin?

Would you even consider trabectedin in this case given its cardiotoxicity?

2 Answers available

Would you discontinue dabrafenib/trametinib in a patient with BRAF mutant metastatic lung cancer if you see mild cardiomyopathy which could be related to the drugs?

Patient does not want chemo but is tolerating these well otherwise.

1 Answer available

Are the cardiac risks of LHRH agonists also seen in patients undergoing bilateral orchiectomy for ADT in hormone-sensitive prostate cancer?

1 Answer available

Do you refer patients to cardiology if they have no history of cardiac disease but will be receiving XRT with high mean doses to the heart?

Is there an established benefit for this? For instance if your patient has cardiac calcifications on imaging but no history of cardiac disease are the...

2 Answers available

How would you approach the management of newly diagnosed metastatic colon cancer in a patient who experienced infusional 5FU-related cardiotoxicity with initial chemotherapy?

When 5FU is a backbone to so many regimens, when (if ever) do you consider re-challenging so as not to abandon an entire line of therapy?

1 Answer available

How would you modify therapy for a metastatic HER2+ breast CA who develops persistent cardiomyopathy after dual HER2 blockade with trastuzumab + pertuzumab?

2 Answers available

What is your approach to adjuvant HER-2 directed therapy in a patient who developed cardiotoxicity following neoadjuvant TC-HP?

Can these patients be re-challenged with Herceptin?

6 Answers available

How do you assess the risk of cardiotoxicity from HER2+ agents?

1 Answer available

What is the rate of a cardiac events that you quote to a patient with preexisting heart disease going on trastuzumab for metastatic Her2+ breast cancer?

How does it vary for patients with a history of hypertension, diabetes, CHF, and coronary artery disease?

1 Answer available

How do you minimize the risk of cardiotoxicity in metastatic Her2 + breast cancer patients who are receiving trastuzumab and have a history of pre-existing cardiac disease?

1 Answer available

How are you using the data on cardiac morbidity in regards to the LV-V5 in breast cancer patients?

Is there a dose constraint you are using for LV-V5?https://www.ncbi.nlm.nih.gov/pubmed/28095159?dopt=Abstract

1 Answer available

When would you consider using radiation for cardiac metastases?

Would you treat if the patient is asymptomatic? If you do treat with RT, what dose-fractionation would you use, and what volumes do you target?

1 Answer available

For a young patient with stage 4 endometrial cancer with an excellent response to anthracyclines, would you continue to give anthracyclines beyond the standard dosage cap if cardiac function remains normal by echocardiogram?

1 Answer available

What is your approach to left sided PMRT in patients with on-going cardiac issues (ie. cardiomyopathy, heart failure, coronary heart disease)?

How do you best counsel their radiation risks?

4 Answers available

How do you counsel men with prostate cancer on the cardiovascular risks of androgen deprivation therapy?

How might a recent (within 6 months) myocardial infarction affect your recommendations?

1 Answer available

Should we be more concerned about cardiac toxicity following breast radiotherapy?

In a case-control study by Darby et al in the New England Journal of Medicine, patients treated for breast cancer with radiation were found to have an...

2 Answers available

Papers discussed in this category

The New England journal of medicine, 2013-03-14

Risk of ischemic heart disease in women after radiotherapy for breast cancer.

JAMA, 2009-08-26

Hormonal therapy use for prostate cancer and mortality in men with coronary artery disease-induced congestive heart failure or myocardial infarction.

European urology, 2015-05

Adverse effects of androgen deprivation therapy and strategies to mitigate them.

JAMA, 2008-01-23

Androgen suppression and radiation vs radiation alone for prostate cancer: a randomized trial.

JAMA oncology, 2016-04

Adverse Health Events Following Intermittent and Continuous Androgen Deprivation in Patients With Metastatic Prostate Cancer.

The New England journal of medicine, 2015-12-17

Ibrutinib as Initial Therapy for Patients with Chronic Lymphocytic Leukemia.

Blood, 2022 Jul 14

Long-term outcomes for ibrutinib-rituximab and chemoimmunotherapy in CLL: updated results of the E1912 trial.

Leukemia, 2021 Apr 27

Pooled analysis of safety data from clinical trials evaluating acalabrutinib monotherapy in mature B-cell malignancies.

J Am Coll Cardiol, 2019 Oct 01

Cardiovascular Toxicities Associated With Ibrutinib.

N. Engl. J. Med., 2013-06-27

Ischemic heart disease after breast cancer radiotherapy.

J. Clin. Oncol., 2017-04-10

Validation and Modification of a Prediction Model for Acute Cardiac Events in Patients With Breast Cancer Treated With Radiotherapy Based on Three-Dimensional Dose Distributions to Cardiac Substructures.

Cochrane Database Syst Rev, 2008 Apr 16

Cardioprotective interventions for cancer patients receiving anthracyclines.

Eur. J. Cancer, 2013 May 22

Role of cardioprotective therapy for prevention of cardiotoxicity with chemotherapy: a systematic review and meta-analysis.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006-09-01

Long-term cardiac tolerability of trastuzumab in metastatic breast cancer: the M.D. Anderson Cancer Center experience.

Breast cancer research and treatment, 2019-05

Cardiac outcomes of trastuzumab therapy in patients with HER2-positive breast cancer and reduced left ventricular ejection fraction.

Clin Colorectal Cancer, 2018 Oct 10

Bolus 5-fluorouracil (5-FU) In Combination With Oxaliplatin Is Safe and Well Tolerated in Patients Who Experienced Coronary Vasospasm With Infusional 5-FU or Capecitabine.

Mayo Clin Proc Innov Qual Outcomes, 2019 Nov 22

Heart Block Caused by Cardiac Metastasis From Merkel Cell Carcinoma: A Case Report.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1997-06

High-dose ifosfamide in bone and soft tissue sarcomas: results of phase II and pilot studies--dose-response and schedule dependence.

The New England journal of medicine, 2014-11-13

Combined BRAF and MEK inhibition versus BRAF inhibition alone in melanoma.

Lancet Oncol., 2017 Sep 11

Dabrafenib plus trametinib in patients with previously untreated BRAF-mutant metastatic non-small-cell lung cancer: an open-label, phase 2 trial.

The Lancet. Oncology, 2017-08

Cardiotoxic effects of anthracycline-based therapy: what is the evidence and what are the potential harms?

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2017-03-10

Prevention and Monitoring of Cardiac Dysfunction in Survivors of Adult Cancers: American Society of Clinical Oncology Clinical Practice Guideline.

International journal of radiation oncology, biology, physics, 2016-11-15

Androgen Deprivation Therapy Use in the Setting of High-dose Radiation Therapy and the Risk of Prostate Cancer-Specific Mortality Stratified by the Extent of Competing Mortality.

Semin Arthritis Rheum, 2020 Jun

TNF-alpha inhibition for the treatment of cardiac sarcoidosis.

Intern Med, 2014 Dec 01

Treatment with methotrexate and low-dose corticosteroids in sarcoidosis patients with cardiac lesions.

J Am Heart Assoc, 2019 Sep 06

Long-Term Corticosteroid-Sparing Immunosuppression for Cardiac Sarcoidosis.

Clin Rheumatol, 2007 Mar 30

Cardiac sarcoidosis responding to monotherapy with infliximab.

Clinical cancer research : an official journal of the American Association for Cancer Research, 2018-12-01

Pathological Response and Survival in Triple-Negative Breast Cancer Following Neoadjuvant Carboplatin plus Docetaxel.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015-08-20

Late Mortality After Dexrazoxane Treatment: A Report From the Children's Oncology Group.

J Clin Oncol, 2020 Apr 28

Effect of Dexrazoxane on Left Ventricular Systolic Function and Treatment Outcomes in Patients With Acute Myeloid Leukemia: A Report From the Children's Oncology Group.

Blood, 2009-09-03

A risk-adapted, response-based approach using ABVE-PC for children and adolescents with intermediate- and high-risk Hodgkin lymphoma: the results of P9425.

Int J Clin Pract, 2021 Mar 24

Effect of COVID-19 medications on corrected QT interval and induction of torsade de pointes: Results of a multicenter national survey.

Mod Rheumatol, 2021 Feb 09

QTc interval prolongation in patients with systemic lupus erythematosus treated with hydroxychloroquine.

Heart Rhythm, 2020 Jun 28

Effects of hydroxychloroquine treatment on QT interval.

Stroke, 2020 Aug 06

Anticoagulation Type and Early Recurrence in Cardioembolic Stroke: The IAC Study.

Clin Cancer Res, 2021 Mar 25

Interim Analysis of the Phase II Study: Noninferiority Study of Doxorubicin with Upfront Dexrazoxane plus Olaratumab for Advanced or Metastatic Soft-Tissue Sarcoma.

Ann Neurol, 2020 Aug 05

Anticoagulation Timing in Cardioembolic Stroke and Recurrent Event Risk.

J Am Coll Cardiol,

Prospective randomized evaluation of the Watchman Left Atrial Appendage Closure device in patients with atrial fibrillation versus long-term warfarin therapy: the PREVAIL trial.

Eur Heart J, 2015 Aug 29

2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension: The Joint Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS): Endorsed by: Association for European Paediatric and Congenital Cardiology (AEPC), International Society for Heart and Lung Transplantation (ISHLT).

Eur Respir J, 2019 Jan 24

Diagnosis of pulmonary hypertension.

The New England journal of medicine, 2012-05-17

Warfarin and aspirin in patients with heart failure and sinus rhythm.

The New England journal of medicine, 2018-10-04

Rivaroxaban in Patients with Heart Failure, Sinus Rhythm, and Coronary Disease.

The New England journal of medicine, 2019-05-16

Dabigatran for Prevention of Stroke after Embolic Stroke of Undetermined Source.

Heart, 2019 Apr 08

Anticoagulation therapy in heart failure and sinus rhythm: a systematic review and meta-analysis.

The New England journal of medicine, 2018-03-29

Cardiovascular Safety of Febuxostat or Allopurinol in Patients with Gout.

Annals of Oncology, 2021 Sep 29

Adjuvant Abemaciclib Combined With Endocrine Therapy for High-Risk Early Breast Cancer: Updated Efficacy and Ki-67 Analysis From the monarchE Study.

Med Phys, 2019 Nov 01

Management of radiotherapy patients with implanted cardiac pacemakers and defibrillators: A Report of the AAPM TG-203.

The New England journal of medicine, 2013-03-21

Closure of patent foramen ovale versus medical therapy after cryptogenic stroke.

Neurology, 2013-08-13

An index to identify stroke-related vs incidental patent foramen ovale in cryptogenic stroke.

The New England journal of medicine, 2017-09-14

Long-Term Outcomes of Patent Foramen Ovale Closure or Medical Therapy after Stroke.

Circ Cardiovasc Interv, 2022 Jun 23

Transcatheter Closure of Patent Foramen Ovale in Older Patients With Cryptogenic Thromboembolic Events.

JAMA, 2021 Dec 14

Heterogeneity of Treatment Effects in an Analysis of Pooled Individual Patient Data From Randomized Trials of Device Closure of Patent Foramen Ovale After Stroke.

JAMA Neurol, 2020 Jul 01

Proposal for Updated Nomenclature and Classification of Potential Causative Mechanism in Patent Foramen Ovale-Associated Stroke.

JAMA Neurol, 2022 Nov 01

Association of Atrial Septal Aneurysm and Shunt Size With Stroke Recurrence and Benefit From Patent Foramen Ovale Closure.

Circulation, 2012-09-25

Periprocedural heparin bridging in patients receiving vitamin K antagonists: systematic review and meta-analysis of bleeding and thromboembolic rates.

BMJ, 2021 Jun 09

Postoperative low molecular weight heparin bridging treatment for patients at high risk of arterial thromboembolism (PERIOP2): double blind randomised controlled trial.

Stroke, 2021 May 24

2021 Guideline for the Prevention of Stroke in Patients With Stroke and Transient Ischemic Attack: A Guideline From the American Heart Association/American Stroke Association.

N Engl J Med,

Cardiovascular and Cancer Risk with Tofacitinib in Rheumatoid Arthritis.

JAMA,

Bevacizumab in patients with hereditary hemorrhagic telangiectasia and severe hepatic vascular malformations and high cardiac output.

Ann Intern Med, 2020 Sep 08

Second International Guidelines for the Diagnosis and Management of Hereditary Hemorrhagic Telangiectasia.

JAMA neurology, 2019-04-01

Association of Apolipoprotein E With Intracerebral Hemorrhage Risk by Race/Ethnicity: A Meta-analysis.

Lancet Neurol, 2019 May 23

Cerebral microbleeds and stroke risk after ischaemic stroke or transient ischaemic attack: a pooled analysis of individual patient data from cohort studies.

JAMA Neurol,

Assessment of Incidence and Risk Factors of Intracerebral Hemorrhage Among Participants in the Framingham Heart Study Between 1948 and 2016.

Lancet Neurol, 2018 Jan 10

The Edinburgh CT and genetic diagnostic criteria for lobar intracerebral haemorrhage associated with cerebral amyloid angiopathy: model development and diagnostic test accuracy study.

Eur Heart J,

2018 ESC Guidelines for the management of cardiovascular diseases during pregnancy.

J Urol, 2019 Jun 12

Cardiovascular Morbidity in a Randomized Trial Comparing GnRH Agonist and GnRH Antagonist among Patients with Advanced Prostate Cancer and Preexisting Cardiovascular Disease.

Eur J Heart Fail, 2020 Aug 06

Baseline cardiovascular risk assessment in cancer patients scheduled to receive cardiotoxic cancer therapies: a position statement and new risk assessment tools from the Cardio-Oncology Study Group of the Heart Failure Association of the European Society of Cardiology in collaboration with the International Cardio-Oncology Society.

Eur Heart J Cardiovasc Imaging, 2022 Sep 10

2022 ESC Guidelines on cardio-oncology developed in collaboration with the European Hematology Association (EHA), the European Society for Therapeutic Radiology and Oncology (ESTRO) and the International Cardio-Oncology Society (IC-OS).

Journal of oncology practice, 2017-04

Prevention and Monitoring of Cardiac Dysfunction in Survivors of Adult Cancers: American Society of Clinical Oncology Clinical Practice Guideline Summary.

J Am Coll Cardiol, 2019 Jan 28

2019 AHA/ACC/HRS Focused Update of the 2014 AHA/ACC/HRS Guideline for the Management of Patients With Atrial Fibrillation: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society.

Stroke, 2019-06

Perioperative/Postoperative Atrial Fibrillation and Risk of Subsequent Stroke and/or Mortality.

J Am Coll Cardiol, 2014 Mar 28

2014 AHA/ACC/HRS guideline for the management of patients with atrial fibrillation: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the Heart Rhythm Society.

N Engl J Med, 2019 Mar 18

Early or Delayed Cardioversion in Recent-Onset Atrial Fibrillation.

JACC Cardiovasc Interv, 2017 Jul 19

Clinical Impact of Baseline Right Bundle Branch Block in Patients Undergoing Transcatheter Aortic Valve Replacement.

Struct Heart, 2022 Mar 17

Risk Stratification and Management of Advanced Conduction Disturbances Following TAVI in Patients With Pre-Existing RBBB.

J Am Coll Cardiol, 2019 Aug 27

Management of Conduction Disturbances Associated With Transcatheter Aortic Valve Replacement: JACC Scientific Expert Panel.

Heart rhythm, 2019-11

2019 HRS expert consensus statement on evaluation, risk stratification, and management of arrhythmogenic cardiomyopathy.

Heart Rhythm, 2015 Sep 30

Nadolol decreases the incidence and severity of ventricular arrhythmias during exercise stress testing compared with β1-selective β-blockers in patients with catecholaminergic polymorphic ventricular tachycardia.

J Am Coll Cardiol, 2009 Aug 25

The year in review of clinical cardiac electrophysiology.

Circulation, 1992 Jul

Efficacy of antiarrhythmic drugs in patients with arrhythmogenic right ventricular disease. Results in patients with inducible and noninducible ventricular tachycardia.

Circulation, 2022 Apr 01

2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure: Executive Summary: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.

JACC Heart Fail, 2022 Dec

How to Initiate and Uptitrate GDMT in Heart Failure: Practical Stepwise Approach to Optimization of GDMT.

Lancet, 2020 Nov 13

Ferric carboxymaltose for iron deficiency at discharge after acute heart failure: a multicentre, double-blind, randomised, controlled trial.

ESC Heart Fail, 2018 Jan 18

Single-dose intravenous iron in Southeast Asian heart failure patients: A pilot randomized placebo-controlled study (PRACTICE-ASIA-HF).

JAMA, 2022 Feb 01

Prevalence and Cumulative Risk of Familial Idiopathic Dilated Cardiomyopathy.

JAMA, 2016-06-28

Intensive vs Standard Blood Pressure Control and Cardiovascular Disease Outcomes in Adults Aged ≥75 Years: A Randomized Clinical Trial.

JAMA, 2019-02-12

Effect of Intensive vs Standard Blood Pressure Control on Probable Dementia: A Randomized Clinical Trial.

Circulation, 2016-11-22

Recommendations for Management of Clinically Significant Drug-Drug Interactions With Statins and Select Agents Used in Patients With Cardiovascular Disease: A Scientific Statement From the American Heart Association.

JAMA, 2022 Apr 26

Aspirin Use to Prevent Cardiovascular Disease: US Preventive Services Task Force Recommendation Statement.

Journal of the American College of Cardiology, 2023 Nov 21

Long-Term Outcomes of Invasive vs Conservative Strategies for Older Patients With Non-ST-Segment Elevation Acute Coronary Syndromes.

The New England journal of medicine, 2023 Aug 26

Complete or Culprit-Only PCI in Older Patients with Myocardial Infarction.

JACC. Cardiovascular interventions, 2014-07

Futility, benefit, and transcatheter aortic valve replacement.

Struct Heart, 2022 Oct 31

Left Atrial-Veno-Arterial Extracorporeal Membrane Oxygenation: Step-By-Step Procedure and Case Example.

Neth Heart J, 2020 Feb

Global longitudinal strain to predict left ventricular dysfunction in asymptomatic patients with severe mitral valve regurgitation: literature review.

Presse Med, 2011 Oct 05

[Benfluorex and valvular heart disease].

Journal of cardiovascular imaging, 2018 Jun 22

Antihypertensive Treatment in Severe Aortic Stenosis.

European heart journal, 2017 Sep 14

Bromocriptine for the treatment of peripartum cardiomyopathy: a multicentre randomized study.

European heart journal, 2020 Oct 14

Clinical presentation, management, and 6-month outcomes in women with peripartum cardiomyopathy: an ESC EORP registry.

Circulation, 2022 Jul 07

Escalating and De-escalating Temporary Mechanical Circulatory Support in Cardiogenic Shock: A Scientific Statement From the American Heart Association.

Journal of the American College of Cardiology, 2018-09-25

Positive Pressure Ventilation in the Cardiac Intensive Care Unit.

Circulation, 2011-08-09

Interpretation of the electrocardiogram of young athletes.

British journal of sports medicine, 2017-05

International criteria for electrocardiographic interpretation in athletes: Consensus statement.

J Am Coll Cardiol, 2020 Sep 29

Time Course of LDL Cholesterol Exposure and Cardiovascular Disease Event Risk.

N Engl J Med, 2020 Nov 16

Phase 3 Trial of Interleukin-1 Trap Rilonacept in Recurrent Pericarditis.

Circulation, 2020 Dec 17

2020 ACC/AHA Guideline for the Management of Patients With Valvular Heart Disease: Executive Summary: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.

Hypertension (Dallas, Tex. : 1979), 2017 Nov 13

2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines.

Pacing Clin Electrophysiol, 2015 Jan 20

Risk of device malfunction in cancer patients with implantable cardiac device undergoing radiotherapy: a population-based cohort study.

JACC CardioOncol, 2021 Sep 21

How to Manage Patients With Cardiac Implantable Electronic Devices Undergoing Radiation Therapy.

Circulation, 2013 Dec 24

Effects of external electrical and magnetic fields on pacemakers and defibrillators: from engineering principles to clinical practice.

Herz, 2014 Dec

[The 2014 ESC guidelines on the diagnosis and management of hypertrophic cardiomyopathy : what is new?].

Trends in cardiovascular medicine, 2019-04

Peripartum cardiomyopathy-diagnosis, management, and long term implications.

European heart journal, 2021 Aug 21

Peripartum cardiomyopathy: from genetics to management.

Cardiac failure review, 2018 Aug

Postpartum Cardiomyopathy and Considerations for Breastfeeding.

Eur Heart J, 2022 Nov 01

JACC CardioOncol, 2022 Dec 20

Immune Checkpoint Inhibitor Myocarditis Treatment Strategies and Future Directions.

J Am Coll Cardiol, 2018 Nov 06

2018 ACC/AHA/HRS Guideline on the Evaluation and Management of Patients With Bradycardia and Cardiac Conduction Delay: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines, and the Heart Rhythm Society.

N Engl J Med, 2013 Apr 25

Biventricular pacing for atrioventricular block and systolic dysfunction.

Circulation, 2022 Apr 01

2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.

J Card Fail, 2021 May 26

Captopril Versus Hydralazine-Isosorbide Dinitrate Vasodilator Protocols in Patients With Acute Decompensated Heart Failure Transitioning From Sodium Nitroprusside.

N Engl J Med, 2012 Jun 28

Early surgery versus conventional treatment for infective endocarditis.

Autoimmunity reviews, 2017-09

Clinical and pathologic implications of extending the spectrum of maternal autoantibodies reactive with ribonucleoproteins associated with cutaneous and now cardiac neonatal lupus from SSA/Ro and SSB/La to U1RNP.

Circulation, 2021 Oct 28

2021 AHA/ACC/ASE/CHEST/SAEM/SCCT/SCMR Guideline for the Evaluation and Diagnosis of Chest Pain: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.

JAMA, 2020 Dec 15

Association Between Adherence to Fractional Flow Reserve Treatment Thresholds and Major Adverse Cardiac Events in Patients With Coronary Artery Disease.

J Am Coll Cardiol, 2020 Jun 09

Survival of Patients With Angina Pectoris Undergoing Percutaneous Coronary Intervention With Intracoronary Pressure Wire Guidance.

Clinical medicine & research, 2013-12

The role of enhanced external counter pulsation therapy in clinical practice.

The Journal of thoracic and cardiovascular surgery, 2017-12

Contracts with people who inject drugs following valve surgery: Unrealistic and misguided expectations.

Tex Heart Inst J, 2022 Nov 1

Use of AngioVac Vacuum Aspiration for Refractory Endocarditis in a Postoperative Mustard Patient.

Catheter Cardiovasc Interv, 2022 Jul 26

Treatment of cardiac device-related infective endocarditis utilizing the new T20 curve catheter and flow saver with the Inari mechanical aspiration system.

Multimed Man Cardiothorac Surg, 2020 Sep 25

Percutaneous aspiration of vegetation from tricuspid valve infective endocarditis.

JACC Case Rep, 2022 May 04

Case Series of Percutaneous Mechanical Aspiration of Mitral Valve Endocarditis.

Circulation, 2015 Sep 15

Infective Endocarditis in Adults: Diagnosis, Antimicrobial Therapy, and Management of Complications: A Scientific Statement for Healthcare Professionals From the American Heart Association.

European heart journal, 2017-05-01

Duration of device-detected subclinical atrial fibrillation and occurrence of stroke in ASSERT.

Circulation, 2018-01-16

Treatment of Subclinical Atrial Fibrillation: Does One Plus One Always Equal Two?

N Engl J Med, 2012 Jan 12

Subclinical atrial fibrillation and the risk of stroke.

J Am Coll Cardiol, 2023 Feb 24

Three-Year Outcomes After Transcatheter or Surgical Aortic Valve Replacement in Low-Risk Patients with Aortic Stenosis.

J Am Coll Cardiol, 2023 Feb 16

Efficacy and safety of the oral PCSK9 inhibitor MK-0616: a phase 2b randomized controlled trial.

N Engl J Med, 2023 Mar 05

Five-Year Follow-up after Transcatheter Repair of Secondary Mitral Regurgitation.

J Am Coll Cardiol, 2021 Feb 02

Feasibility Study of the Transcatheter Valve Repair System for Severe Tricuspid Regurgitation.

Journal of the American College of Cardiology, 2013-07-23

Treatment of obstructive sleep apnea reduces the risk of atrial fibrillation recurrence after catheter ablation.

Lancet, 2021 Aug 27

Implantable loop recorder detection of atrial fibrillation to prevent stroke (The LOOP Study): a randomised controlled trial.

N Engl J Med, 2018 Feb 01

Catheter Ablation for Atrial Fibrillation with Heart Failure.

Cardiovasc Drugs Ther, 2021 Sep 07

Is It Safe (and When) to Stop Oral Anticoagulation After Ablation for Atrial fibrillation? (Do We Have Enough Evidence to Solve the Dilemma?).

Journal of clinical lipidology, 2008-10

Curr Rheumatol Rep, 2020 Aug 26

Lipid-lowering Therapies in Myositis.

Circulation. Arrhythmia and electrophysiology, 2014-04

Guidelines for management of asymptomatic ventricular pre-excitation: brave new world or Pandora's box?

Circulation. Arrhythmia and electrophysiology, 2015-12

Long-Term Natural History of Adult Wolff-Parkinson-White Syndrome Patients Treated With and Without Catheter Ablation.

Heart Rhythm, 2020 Jun 01

Loss of ventricular preexcitation during noninvasive testing does not exclude high-risk accessory pathways: A multicenter study of WPW in children.

J Geriatr Cardiol, 2017 Oct

Reversal of Wolff-Parkinson-White Syndrome induced dilated cardiomyopathy via resynchronization and subsequent accessory pathway ablation.

The American journal of cardiology, 2018-12-01

Meta-Analysis of Carvedilol for the Prevention of Anthracycline-Induced Cardiotoxicity.

Curr Oncol, 2021 Oct 13

Exercise to Reduce Anthracycline-Mediated Cardiovascular Complications in Breast Cancer Survivors.

Cardiooncology, 2019 Jan 29

Upfront dexrazoxane for the reduction of anthracycline-induced cardiotoxicity in adults with preexisting cardiomyopathy and cancer: a consecutive case series.

Haematologica, 2010-07

Sex differences in the JAK2 V617F allele burden in chronic myeloproliferative disorders.

The American journal of medicine, 1997-01

Inapparent polycythemia vera: an unrecognized diagnosis.

Haematologica, 2019 Aug 14

Masked polycythemia vera: analysis of a single center cohort of 2480 red cell masses.

Journal of the American College of Cardiology, 2014-09-09

Reply: Ejection fraction may improve but the scar still exists! The risk may be lower but not zero.

J Am Coll Cardiol, 2014 Apr 09

Appropriateness of primary prevention implantable cardioverter-defibrillators at the time of generator replacement: are indications still met?

J Am Heart Assoc, 2019 Oct 02

Extended Duration of Dual-Antiplatelet Therapy After Percutaneous Coronary Intervention: How Long Is Too Long?

Circulation, 2022 Nov 07

Aspirin Versus Clopidogrel for Long-Term Maintenance Monotherapy After Percutaneous Coronary Intervention: The HOST-EXAM Extended Study.

Pediatr Transplant, 2021 Aug

Treatment of post-transplant lymphoproliferative disorder (PTLD) in a heart transplant recipient with chimeric antigen receptor T-cell therapy.

Br J Haematol, 2023 May 2

Real-world evidence of the safety and survival with CD19 CAR-T cell therapy for relapsed/refractory solid organ transplant-related PTLD.

Bone marrow transplantation, 2022 Dec 27

CD19 CAR-T therapy in solid organ transplant recipients: case report and systematic review.

Eur Heart J, 2022 Jan 31

Defining cardiovascular toxicities of cancer therapies: an International Cardio-Oncology Society (IC-OS) consensus statement.

Blood advances, 2018-05-22

Epidemiology of AL amyloidosis: a real-world study using US claims data.

JACC CardioOncol, 2020 Mar 17

Plasma Hepatocyte Growth Factor for Diagnosis and Prognosis in Light Chain and Transthyretin Cardiac Amyloidosis.

Mayo Clin Proc, 2010 Aug 16

Prevalence of monoclonal gammopathy of undetermined significance: a systematic review.

ESC Heart Fail, 2021 Dec 08

Echocardiographic and clinical predictors of cardiac amyloidosis: limitations of apical sparing.

J Thorac Cardiovasc Surg, 2021 May 08

2020 ACC/AHA guideline for the management of patients with valvular heart disease: A report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.

JACC CardioOncol, 2021 Sep 21

Cardiovascular Manifestations From Therapeutic Radiation: A Multidisciplinary Expert Consensus Statement From the International Cardio-Oncology Society.

J Am Heart Assoc, 2020 Jan 21

Immune Checkpoint Inhibitor Myocarditis: Pathophysiological Characteristics, Diagnosis, and Treatment.

Circulation, 2020 Jun 15

Major Adverse Cardiovascular Events and the Timing and Dose of Corticosteroids in Immune Checkpoint Inhibitor-Associated Myocarditis.

The New England journal of medicine, 2002-02-21

Treatment of comatose survivors of out-of-hospital cardiac arrest with induced hypothermia.

N Engl J Med, 2013 Nov 17

Targeted temperature management at 33°C versus 36°C after cardiac arrest.

Cureus, 2022 Sep 11

Targeted Temperature Management After Cardiac Arrest: A Systematic Review.

Crit Care, 2020 Jan 06

High Quality Targeted Temperature Management (TTM) After Cardiac Arrest.

JAMA Cardiol, 2022 Nov 01

Long-term Effects of P2Y12 Inhibitor Monotherapy After Percutaneous Coronary Intervention: 3-Year Follow-up of the SMART-CHOICE Randomized Clinical Trial.

JAMA, 2001-05-09

Prevalence of diagnosed atrial fibrillation in adults: national implications for rhythm management and stroke prevention: the AnTicoagulation and Risk Factors in Atrial Fibrillation (ATRIA) Study.

The American journal of cardiology, 2015-12-15

Frequent Atrial Premature Complexes and Their Association With Risk of Atrial Fibrillation.

Journal of electrocardiology, 2018

Frequent premature atrial complexes as a predictor of atrial fibrillation: Systematic review and meta-analysis.

N Engl J Med, 2017 Mar 17

Evolocumab and Clinical Outcomes in Patients with Cardiovascular Disease.

JAMA Cardiol,

Off-label Use of Direct Oral Anticoagulants Compared With Warfarin for Left Ventricular Thrombi.

Eur Heart J Cardiovasc Pharmacother, 2022 Sep 29

Apixaban vs. warfarin in patients with left ventricular thrombus: a prospective multicentre randomized clinical trial‡.

Eur Heart J Cardiovasc Pharmacother, 2021 Sep 21

The use of novel oral anticoagulants compared to vitamin K antagonists (warfarin) in patients with left ventricular thrombus after acute myocardial infarction.

ESC Heart Fail, 2020 Jun 25

Direct oral anticoagulants compared to vitamin K antagonist for the management of left ventricular thrombus.

The New England journal of medicine, 2018-02-15

Outcomes after Angiography with Sodium Bicarbonate and Acetylcysteine.

J Am Coll Cardiol, 2023 Apr 04

Early Lead Extraction for Infected Implanted Cardiac Electronic Devices: JACC Review Topic of the Week.

Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 2017 Oct 09

Clinical recommendations for cardiovascular magnetic resonance mapping of T1, T2, T2* and extracellular volume: A consensus statement by the Society for Cardiovascular Magnetic Resonance (SCMR) endorsed by the European Association for Cardiovascular Imaging (EACVI).

Circulation, 2011 Feb 14

Effectiveness-based guidelines for the prevention of cardiovascular disease in women--2011 update: a guideline from the american heart association.

Circulation. Cardiovascular quality and outcomes, 2017 Feb 22

Preeclampsia and Future Cardiovascular Health: A Systematic Review and Meta-Analysis.

Clinical science (London, England : 1979), 2012 Jul

Pre-eclampsia and offspring cardiovascular health: mechanistic insights from experimental studies.

Circulation, 2016-03-08

Swimming-Induced Pulmonary Edema: Pathophysiology and Risk Reduction With Sildenafil.

The Physician and sportsmedicine, 2018 Nov 17

A literature review of immersion pulmonary edema.

Journal of cardiac failure, 2023 Jun 22

Variation in Hemodynamic Assessment and Interpretation: A Call to Standardize the Right Heart Catheterization.

Lancet (London, England), 2015 Jul 15

Small bites versus large bites for closure of abdominal midline incisions (STITCH): a double-blind, multicentre, randomised controlled trial.

The New England journal of medicine, 2020 Mar 30

Initial Invasive or Conservative Strategy for Stable Coronary Disease.

Circulation. Cardiovascular quality and outcomes, 2020 Mar 10

Suboptimal Management of Cardiovascular Risk Factors Among Non-US-Citizen Immigrants: Time to Build a Healthier Immigrant Workforce in the United States.

JAMA cardiology, 2021 Feb 01

Value of Coronary Artery Calcium Scanning in Association With the Net Benefit of Aspirin in Primary Prevention of Atherosclerotic Cardiovascular Disease.

The New England journal of medicine, 2015 Sep 17

Empagliflozin, Cardiovascular Outcomes, and Mortality in Type 2 Diabetes.

The New England journal of medicine, 2020 Sep 24

Dapagliflozin in Patients with Chronic Kidney Disease.

Heart rhythm, 2020 Jul 25

Clinical significance of myocardial scar in patients with frequent premature ventricular complexes undergoing catheter ablation.

JACC. Clinical electrophysiology, 2022 Apr 28

Short-Coupled Idiopathic Ventricular Fibrillation: A Literature Review With Extended Follow-Up.

Circulation, 2019 Jan 29

Open-Label Randomized Trial Comparing Oral Anticoagulation With and Without Single Antiplatelet Therapy in Patients With Atrial Fibrillation and Stable Coronary Artery Disease Beyond 1 Year After Coronary Stent Implantation.

The New England journal of medicine, 2000-06-29

Electrophysiologic testing to identify patients with coronary artery disease who are at risk for sudden death. Multicenter Unsustained Tachycardia Trial Investigators.

The New England journal of medicine, 2011-09-15

Apixaban versus warfarin in patients with atrial fibrillation.

The New England journal of medicine, 2011 Aug 10

Rivaroxaban versus warfarin in nonvalvular atrial fibrillation.

The New England journal of medicine, 2009 Aug 30

Dabigatran versus warfarin in patients with atrial fibrillation.

EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2019 Jun 20

Percutaneous recanalisation of chronic total occlusions: 2019 consensus document from the EuroCTO Club.

EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2022 Sep 20

Recanalisation of coronary chronic total occlusions.

Circulation, 2011 Jul 25

Mobile thrombus on device leads in patients undergoing ablation: identification, incidence, location, and association with increased pulmonary artery systolic pressure.

The New England journal of medicine, 2001-08-16

Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation.

The Annals of thoracic surgery, 2017 Feb 04

Surgical Versus Medical Therapy for Prosthetic Valve Endocarditis: A Meta-Analysis of 32 Studies.

European heart journal, 2023 Oct 14

2023 ESC Guidelines for the management of endocarditis.

The New England journal of medicine, 2023 Aug 27

Timing of Complete Revascularization with Multivessel PCI for Myocardial Infarction.

Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG, 2014-04-18

The WASOG Sarcoidosis Organ Assessment Instrument: An update of a previous clinical tool.

Heart rhythm, 2014-07

HRS expert consensus statement on the diagnosis and management of arrhythmias associated with cardiac sarcoidosis.

Circulation journal : official journal of the Japanese Circulation Society, 2019 Oct 09

JCS 2016 Guideline on Diagnosis and Treatment of Cardiac Sarcoidosis　- Digest Version.

The New England journal of medicine, 2023 Aug 27

Catheter Ablation in End-Stage Heart Failure with Atrial Fibrillation.

JACC. Clinical electrophysiology, 2021 Feb 24

Atrial Fibrillation Burden and Clinical Outcomes in Heart Failure: The CASTLE-AF Trial.

Journal of the American Heart Association, 2024 Jan 19

Impella Versus Intra-Aortic Balloon Pump in Patients With Cardiogenic Shock Treated With Venoarterial Extracorporeal Membrane Oxygenation: An Observational Study.

Perfusion, 2021 Jul 28

Veno-arterial extracorporeal membrane oxygenation with concomitant Impella versus concomitant intra-aortic-balloon-pump for cardiogenic shock.

Current problems in cardiology, 2022 Sep 26

Impella Versus Extracorporeal Membranous Oxygenation (ECMO) for Cardiogenic Shock: A Systematic Review and Meta-analysis.

Circulation. Cardiovascular imaging, 2018-03

Computed Tomography Aortic Valve Calcium Scoring in Patients With Aortic Stenosis.

Circulation, 2023 Aug 27

Safety of Switching from a Vitamin K Antagonist to a Non-Vitamin K Antagonist Oral Anticoagulant in Frail Older Patients with Atrial Fibrillation: Results of the FRAIL-AF Randomized Controlled Trial.

The New England journal of medicine, 2020 Mar 28

Rivaroxaban in Peripheral Artery Disease after Revascularization.

European heart journal, 2023 Jun 09

Pre-treatment bicarbonate levels and decongestion by acetazolamide: the ADVOR trial.

The New England journal of medicine, 2022 Aug 27

Acetazolamide in Acute Decompensated Heart Failure with Volume Overload.

Lupus, 2018 Oct 05

Resolution of large aortic valve vegetations in antiphospholipid syndrome treated with therapeutic anticoagulation: a report of two cases and literature review.

The New England journal of medicine, 2001-11-15

Long-term use of a left ventricular assist device for end-stage heart failure.

International journal of cardiology, 2023 Aug 01

Edge to edge mitral valve repair beyond COAPT criteria: A bridge to further therapies for patients with advanced heart failure.

Lancet (London, England), 2023 Mar 06

Inflammation and cholesterol as predictors of cardiovascular events among patients receiving statin therapy: a collaborative analysis of three randomised trials.

The New England journal of medicine, 2023 Nov 11

Restrictive or Liberal Transfusion Strategy in Myocardial Infarction and Anemia.

Circulation. Heart failure, 2021 Dec 20

Long-Term Survival With Tafamidis in Patients With Transthyretin Amyloid Cardiomyopathy.

The New England journal of medicine, 2023 Aug 25

Semaglutide in Patients with Heart Failure with Preserved Ejection Fraction and Obesity.

HeartRhythm case reports, 2016-09

Abdominal implantable cardioverter-defibrillator placement in a patient requiring bilateral chest radiation therapy.

Circulation, 2023 Nov 13

Sudden Cardiac Death in National Collegiate Athletic Association Athletes: A 20-Year Study.

Circulation, 2023 Nov 11

Arrhythmic Risk In Biventricular Pacing Compared with Left Bundle Branch Area Pacing: Results From The International LBBAP Collaborative Study (I-CLAS).

Circulation. Cardiovascular quality and outcomes, 2023 Nov 06

Off-Label Dosing of Direct Oral Anticoagulants Among Inpatients with Atrial Fibrillation in the United States.

American heart journal, 2017 Apr 24

Rationale and design of the Apixaban for the Reduction of Thrombo-Embolism in Patients With Device-Detected Sub-Clinical Atrial Fibrillation (ARTESiA) trial.

The New England journal of medicine, 2023 Nov 11

Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes.

American heart journal, 2023 Mar 25

Screening for peripartum cardiomyopathies using artificial intelligence in Nigeria (SPEC-AI Nigeria): Clinical trial rationale and design.

JAMA, 2023 Nov 11

Aspirin and Hemocompatibility Events With a Left Ventricular Assist Device in Advanced Heart Failure: The ARIES-HM3 Randomized Clinical Trial.

Arrhythmia & electrophysiology review, 2020 Dec

Management of Cardiac Sarcoidosis in 2020.

Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2020 Sep 09

Usefulness of oral anticoagulation in patients with coronary aneurysms: Insights from the CAAR registry.

Circulation research, 2019 Feb

Synergy of Dual Pathway Inhibition in Chronic Cardiovascular Disease.

Journal of the American College of Cardiology, 2020 Aug 11

Heart Failure With Recovered Left Ventricular Ejection Fraction: JACC Scientific Expert Panel.

Lancet (London, England), 2018 Nov 11

Withdrawal of pharmacological treatment for heart failure in patients with recovered dilated cardiomyopathy (TRED-HF): an open-label, pilot, randomised trial.

The Journal of innovations in cardiac rhythm management, 2020 May 15

Navigating Challenging Left Ventricular Lead Placements for Cardiac Resynchronization Therapy.

Cardiology, 2021 Nov 29

Strategy for Failed Transvenous Left-Ventricular Lead Placement in Cardiac Resynchronization Therapy: Surrender or Struggle?

Journal of the American Heart Association, 2021 Sep 06

Radiation-Induced Cardiovascular Disease: Review of an Underrecognized Pathology.

The New England journal of medicine, 2023 Aug 25

Anticoagulation with Edoxaban in Patients with Atrial High-Rate Episodes.

Journal of the American College of Cardiology, 1998-07

Is hospital admission for initiation of antiarrhythmic therapy with sotalol for atrial arrhythmias required? Yield of in-hospital monitoring and prediction of risk for significant arrhythmia complications.

JACC. Heart failure, 2020 Feb 05

Real World Use of Hypertonic Saline in Refractory Acute Decompensated Heart Failure: A U.S. Center's Experience.

Medwave, 2015 Aug 27

What are the effects of hypertonic saline plus furosemide in acute heart failure?

Clinical cardiology, 2023 Jun 20

The added value of hypertonic saline solution to furosemide monotherapy in patients with acute decompensated heart failure: A meta-analysis and trial sequential analysis.

American journal of physiology. Renal physiology, 2021 May 10

Induction of renal tumor necrosis factor-α and other autacoids and the beneficial effects of hypertonic saline in acute decompensated heart failure.

The British journal of cardiology, 2022 Jul 19

Age and the power of zero CAC in cardiac risk assessment: overview of the literature and a cautionary case.

Journal of clinical lipidology, 2020 Jan 02

Coronary artery disease with normal lipids and low coronary artery calcium in two women with high lipoprotein(a).

Circulation, 2016-09-06

2016 ACC/AHA Guideline Focused Update on Duration of Dual Antiplatelet Therapy in Patients With Coronary Artery Disease: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines: An Update of the 2011 ACCF/AHA/SCAI Guideline for Percutaneous Coronary Intervention, 2011 ACCF/AHA Guideline for Coronary Artery Bypass Graft Surgery, 2012 ACC/AHA/ACP/AATS/PCNA/SCAI/STS Guideline for the Diagnosis and Management of Patients With Stable Ischemic Heart Disease, 2013 ACCF/AHA Guideline for the Management of ST-Elevation Myocardial Infarction, 2014 AHA/ACC Guideline for the Management of Patients With Non-ST-Elevation Acute Coronary Syndromes, and 2014 ACC/AHA Guideline on Perioperative Cardiovascular Evaluation and Management of Patients Undergoing Noncardiac Surgery.

Circulation, 2023 Mar 16

Evaluation and Management of Pulmonary Hypertension in Noncardiac Surgery: A Scientific Statement From the American Heart Association.

Journal of the American College of Cardiology, 2022 May 03

Survival Following Alcohol Septal Ablation or Septal Myectomy for Patients With Obstructive Hypertrophic Cardiomyopathy.

Clinical cardiology, 2020 Feb 19

Beta-blockers withdrawal in patients with heart failure with preserved ejection fraction and chronotropic incompetence: Effect on functional capacity rationale and study design of a prospective, randomized, controlled trial (The Preserve-HR trial).

PloS one, 2023 Nov 16

Effects of beta-blocker withdrawal in patients with heart failure with preserved ejection fraction: A protocol for systematic review and meta-analysis.

Heart rhythm, 2019-01

Identification of paroxysmal atrial fibrillation subtypes in over 13,000 individuals.

Pacing and clinical electrophysiology : PACE, 2019-07

Reactive atrial-based antitachycardia pacing therapy reduces atrial tachyarrhythmias.

Heart rhythm, 2015 Apr 11

New-generation atrial antitachycardia pacing (Reactive ATP) is associated with reduced risk of persistent or permanent atrial fibrillation in patients with bradycardia: Results from the MINERVA randomized multicenter international trial.

Circulation, 2023 Nov 30

2023 ACC/AHA/ACCP/HRS Guideline for the Diagnosis and Management of Atrial Fibrillation: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.

The New England journal of medicine, 2023 Nov 12

Apixaban for Stroke Prevention in Subclinical Atrial Fibrillation.

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2012 Mar

Review of atrial fibrillation outcome trials of oral anticoagulant and antiplatelet agents.

The New England journal of medicine, 1991-03-21

Mortality and morbidity in patients receiving encainide, flecainide, or placebo. The Cardiac Arrhythmia Suppression Trial.

Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2022 Apr 02

Propafenone use in coronary artery disease patients undergoing atrial fibrillation ablation.

Journal of clinical medicine, 2021 Apr 02

Flecainide How and When: A Practical Guide in Supraventricular Arrhythmias.

Journal of the American College of Cardiology, 2023 Jan 31

Infective Endocarditis After Transcatheter Aortic Valve Replacement: JACC State-of-the-Art Review.

JACC. Cardiovascular interventions, 2022 Jun 13

Long-Term Follow-Up of Hypoattenuated Leaflet Thickening After Transcatheter Aortic Valve Replacement.

JACC. Cardiovascular imaging, 2017 Aug 16