Cardiology   

Questions discussed in this category



In the span between the HACA trial (HACA, PMID 11856793) and the Targeted Temperature Management in Out-of-Hospital Cardiac Arrest study (Dankiewicz e...

Patient with negative blood cultures, completed 6 weeks of IV antibiotics and vegetation persists. CT imaging without evidence of malignancy. No evide...

If so, is there a quantitative calcium score or a reported severity of CT coronary artery calcification that would lead you to start daily aspirin?

For radiation oncologists, how do you ameliorate the risk for radiation-related injury to epicardial coronaries during treatment sessions?

Can sotalol initiation for atrial fibrillation be performed safely outpatient, and if so, what would be a reasonable approach to accomplishing this?&n...

If these patients were already prescribed non-selective beta blockers outpatient, do you recommend withholding these medications in the acute phase?&n...

Would you extend length of time for anticoagulation if the apex remained akinetic on surveillance TTEs? 

If delayed complete revascularization is favored, would you consider staged PCI during that same admission or PCI outpatient? 

Do you have a specific protocol you follow during the stress echo, and if so, what echo parameters are you using to evaluate for exercised-induced hea...

In FRAIL-AF, switching VKA therapy to a NOAC was associated with higher risk of bleeding in elderly, frail patients. 

Do you include the amount of IV amiodarone already administered as part of the loading dose? 

If LHC is deferred, would you consider loading with plavix and treating for ACS for 48 hours (assuming acceptable bleeding risk) and optimizing GDMT p...

The basis of the question is that HFrEF trials enroll patients who have Class II-IV symptoms. If their LV systolic function recovers and they become a...

In FRAIL-AF, participants were switched from VKA to dabigatran, rivaroxaban, apixaban, and edoxaban.

If PVC burden exceeded 10-15%, would you offer ablation in the absence of specific symptoms?  

(ie., assessing gait speed, cognition, physical function, fall history, orthostatic vital signs, etc.)

Is there an approach to tapering the other two medications while uptitrating Droxidopa dosing to reduce the risk of supine hypertension?

Recent AHA guidelines state that all women who have had a diagnosis of preeclampsia in a prior pregnancy should receive an evaluation of cardiac risk....

How would you assess response to bempedoic acid and its safety on outpatient labs, and how frequently would you have labs monitored?  

For the first time in my 27-year career, I was asked to consult on a patient in his early 40s with immersion pulmonary edema from scuba diving. &...

While the current guidelines favor early surgery (within 48 hrs of diagnosis) for this population based on the results of the EASE trial (link attache...

Do you insist on ambulatory/home blood pressures to rule in/out white coat hypertension? Does your practice have a system to log patients' BPs to supp...

Assuming the patient is symptomatic and/or has compression of ventricles, what field design and dose-fractionation would you use?

Are there any significant benefits to lowering moderately elevated lipoprotein A levels?

Do you distinguish between primary and secondary prevention? Wilson et al., PMID 31130428 is helpful, but curious how people apply this data in practi...

If the pacemaker receives no dose, what dose are the leads allowed to receive and still function? Should interrogation(s) be done weekly?Does dose per...

Would you bridge with enoxaparin 0.7 mg/kg/day in an ESKD patient, as described in a previous retrospective study (Pon et al., PMID: 24718051)?

If so, how frequently should we measure iron saturation/ferritin levels post-iron infusion?

E.g. in a patient with tenuous cardiac function, would starting treatment several weeks earlier potentially improve outcomes?

Would you continue ibrutinib even if they are placed on anti-platelet therapy such as clopidogrel or ticagrelor? When do you switch to an altern...

Please comment on temperature recommendations and role of exchange transfusion. 

If a patient had prior breast conserving treatment and now has inflammatory breast disease, would you prophylactical send the patient to a cardiologis...

How do you approach secondary stroke prevention for patients with ischemic stroke, atrial fibrillation, and signs of cerebral amyloid angiopathy/micro...

Recent Japanese guidelines recommend <10MV beams, heart rhythm society and AAPM suggest up to 10MV beams are safe, recommending ≤10MV beams. Giv...

Dr. Charles-Schoeman presented data at ACR 21 showing that, paradoxically, there is a U-shaped relationship between inflammation and LDL levels in pat...

Do you feel comfortable with BTK inhibitors in these patients? In ELEVATE-RR patients on a/c were excluded, and rate of atrial fibrillation in the ac...

For a relatively young, medically compliant patient with HFrEF (EF<35%) and h/o embolic stroke, what is the consensus of starting AC for secondary ...

Would you consider using radiotherapy for persistent malignant pericardial effusion?  What dose-fractionation would you use, and what would your ...

Is there an established benefit for this? For instance if your patient has cardiac calcifications on imaging but no history of cardiac disease are the...

When 5FU is a backbone to so many regimens, when (if ever) do you consider re-challenging so as not to abandon an entire line of therapy?

Is there a dose constraint you are using for LV-V5?https://www.ncbi.nlm.nih.gov/pubmed/28095159?dopt=Abstract

Would you treat if the patient is asymptomatic? If you do treat with RT, what dose-fractionation would you use, and what volumes do you target?

How might a recent (within 6 months) myocardial infarction affect your recommendations?

In a case-control study by Darby et al in the New England Journal of Medicine, patients treated for breast cancer with radiation were found to have an...


Papers discussed in this category


The New England journal of medicine, 2013-03-14

JAMA, 2009-08-26

European urology, 2015-05

JAMA, 2008-01-23

JAMA oncology, 2016-04

The New England journal of medicine, 2015-12-17

Blood, 2022 Jul 14

Leukemia, 2021 Apr 27

J Am Coll Cardiol, 2019 Oct 01

N. Engl. J. Med., 2013-06-27

J. Clin. Oncol., 2017-04-10

Cochrane Database Syst Rev, 2008 Apr 16

Eur. J. Cancer, 2013 May 22

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006-09-01

Breast cancer research and treatment, 2019-05

Clin Colorectal Cancer, 2018 Oct 10

Mayo Clin Proc Innov Qual Outcomes, 2019 Nov 22

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1997-06

The New England journal of medicine, 2014-11-13

Lancet Oncol., 2017 Sep 11

The Lancet. Oncology, 2017-08

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2017-03-10

International journal of radiation oncology, biology, physics, 2016-11-15

Semin Arthritis Rheum, 2020 Jun

Intern Med, 2014 Dec 01

J Am Heart Assoc, 2019 Sep 06

Clin Rheumatol, 2007 Mar 30

Clinical cancer research : an official journal of the American Association for Cancer Research, 2018-12-01

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2015-08-20

J Clin Oncol, 2020 Apr 28

Blood, 2009-09-03

Int J Clin Pract, 2021 Mar 24

Mod Rheumatol, 2021 Feb 09

Heart Rhythm, 2020 Jun 28

Stroke, 2020 Aug 06

Clin Cancer Res, 2021 Mar 25

Ann Neurol, 2020 Aug 05

J Am Coll Cardiol,

Eur Heart J, 2015 Aug 29

Eur Respir J, 2019 Jan 24

The New England journal of medicine, 2012-05-17

The New England journal of medicine, 2018-10-04

The New England journal of medicine, 2019-05-16

Heart, 2019 Apr 08

The New England journal of medicine, 2018-03-29

Annals of Oncology, 2021 Sep 29

Med Phys, 2019 Nov 01

The New England journal of medicine, 2013-03-21

Neurology, 2013-08-13

The New England journal of medicine, 2017-09-14

Circ Cardiovasc Interv, 2022 Jun 23

JAMA, 2021 Dec 14

JAMA Neurol, 2020 Jul 01

JAMA Neurol, 2022 Nov 01

Circulation, 2012-09-25

BMJ, 2021 Jun 09

Stroke, 2021 May 24

N Engl J Med,

JAMA,

Ann Intern Med, 2020 Sep 08

JAMA neurology, 2019-04-01

Lancet Neurol, 2019 May 23

JAMA Neurol,

Lancet Neurol, 2018 Jan 10

Eur Heart J,

J Urol, 2019 Jun 12

Eur J Heart Fail, 2020 Aug 06

Eur Heart J Cardiovasc Imaging, 2022 Sep 10

Journal of oncology practice, 2017-04

J Am Coll Cardiol, 2019 Jan 28

Stroke, 2019-06

J Am Coll Cardiol, 2014 Mar 28

N Engl J Med, 2019 Mar 18

JACC Cardiovasc Interv, 2017 Jul 19

Struct Heart, 2022 Mar 17

J Am Coll Cardiol, 2019 Aug 27

Heart rhythm, 2019-11

Heart Rhythm, 2015 Sep 30

J Am Coll Cardiol, 2009 Aug 25

Circulation, 1992 Jul

Circulation, 2022 Apr 01

JACC Heart Fail, 2022 Dec

Lancet, 2020 Nov 13

ESC Heart Fail, 2018 Jan 18

JAMA, 2022 Feb 01

JAMA, 2016-06-28

JAMA, 2019-02-12

Circulation, 2016-11-22

JAMA, 2022 Apr 26

Journal of the American College of Cardiology, 2023 Nov 21

The New England journal of medicine, 2023 Aug 26

JACC. Cardiovascular interventions, 2014-07

Struct Heart, 2022 Oct 31

Neth Heart J, 2020 Feb

Presse Med, 2011 Oct 05

Journal of cardiovascular imaging, 2018 Jun 22

European heart journal, 2017 Sep 14

European heart journal, 2020 Oct 14

Circulation, 2022 Jul 07

Journal of the American College of Cardiology, 2018-09-25

Circulation, 2011-08-09

British journal of sports medicine, 2017-05

J Am Coll Cardiol, 2020 Sep 29

N Engl J Med, 2020 Nov 16

Circulation, 2020 Dec 17

Hypertension (Dallas, Tex. : 1979), 2017 Nov 13

Pacing Clin Electrophysiol, 2015 Jan 20

JACC CardioOncol, 2021 Sep 21

Circulation, 2013 Dec 24

Herz, 2014 Dec

Trends in cardiovascular medicine, 2019-04

European heart journal, 2021 Aug 21

Cardiac failure review, 2018 Aug

Eur Heart J, 2022 Nov 01

JACC CardioOncol, 2022 Dec 20

J Am Coll Cardiol, 2018 Nov 06

N Engl J Med, 2013 Apr 25

Circulation, 2022 Apr 01

J Card Fail, 2021 May 26

N Engl J Med, 2012 Jun 28

Autoimmunity reviews, 2017-09

Circulation, 2021 Oct 28

JAMA, 2020 Dec 15

J Am Coll Cardiol, 2020 Jun 09

Clinical medicine & research, 2013-12

The Journal of thoracic and cardiovascular surgery, 2017-12

Tex Heart Inst J, 2022 Nov 1

Catheter Cardiovasc Interv, 2022 Jul 26

Multimed Man Cardiothorac Surg, 2020 Sep 25

JACC Case Rep, 2022 May 04

Circulation, 2015 Sep 15

European heart journal, 2017-05-01

Circulation, 2018-01-16

N Engl J Med, 2012 Jan 12

J Am Coll Cardiol, 2023 Feb 24

J Am Coll Cardiol, 2023 Feb 16

N Engl J Med, 2023 Mar 05

J Am Coll Cardiol, 2021 Feb 02

Journal of the American College of Cardiology, 2013-07-23

Lancet, 2021 Aug 27

N Engl J Med, 2018 Feb 01

Cardiovasc Drugs Ther, 2021 Sep 07

Journal of clinical lipidology, 2008-10

Curr Rheumatol Rep, 2020 Aug 26

Circulation. Arrhythmia and electrophysiology, 2014-04

Circulation. Arrhythmia and electrophysiology, 2015-12

Heart Rhythm, 2020 Jun 01

J Geriatr Cardiol, 2017 Oct

The American journal of cardiology, 2018-12-01

Curr Oncol, 2021 Oct 13

Cardiooncology, 2019 Jan 29

Haematologica, 2010-07

The American journal of medicine, 1997-01

Haematologica, 2019 Aug 14

Journal of the American College of Cardiology, 2014-09-09

J Am Coll Cardiol, 2014 Apr 09

J Am Heart Assoc, 2019 Oct 02

Circulation, 2022 Nov 07

Pediatr Transplant, 2021 Aug

Br J Haematol, 2023 May 2

Bone marrow transplantation, 2022 Dec 27

Eur Heart J, 2022 Jan 31

Blood advances, 2018-05-22

JACC CardioOncol, 2020 Mar 17

Mayo Clin Proc, 2010 Aug 16

ESC Heart Fail, 2021 Dec 08

J Thorac Cardiovasc Surg, 2021 May 08

JACC CardioOncol, 2021 Sep 21

J Am Heart Assoc, 2020 Jan 21

Circulation, 2020 Jun 15

The New England journal of medicine, 2002-02-21

N Engl J Med, 2013 Nov 17

Cureus, 2022 Sep 11

Crit Care, 2020 Jan 06

JAMA Cardiol, 2022 Nov 01

JAMA, 2001-05-09

The American journal of cardiology, 2015-12-15

Journal of electrocardiology, 2018

N Engl J Med, 2017 Mar 17

JAMA Cardiol,

Eur Heart J Cardiovasc Pharmacother, 2022 Sep 29

Eur Heart J Cardiovasc Pharmacother, 2021 Sep 21

ESC Heart Fail, 2020 Jun 25

The New England journal of medicine, 2018-02-15

J Am Coll Cardiol, 2023 Apr 04

Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 2017 Oct 09

Circulation, 2011 Feb 14

Circulation. Cardiovascular quality and outcomes, 2017 Feb 22

Clinical science (London, England : 1979), 2012 Jul

Circulation, 2016-03-08

The Physician and sportsmedicine, 2018 Nov 17

Journal of cardiac failure, 2023 Jun 22

Lancet (London, England), 2015 Jul 15

The New England journal of medicine, 2020 Mar 30

Circulation. Cardiovascular quality and outcomes, 2020 Mar 10

JAMA cardiology, 2021 Feb 01

The New England journal of medicine, 2015 Sep 17

The New England journal of medicine, 2020 Sep 24

Heart rhythm, 2020 Jul 25

JACC. Clinical electrophysiology, 2022 Apr 28

Circulation, 2019 Jan 29

The New England journal of medicine, 2000-06-29

The New England journal of medicine, 2011-09-15

The New England journal of medicine, 2011 Aug 10

The New England journal of medicine, 2009 Aug 30

EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2019 Jun 20

EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2022 Sep 20

Circulation, 2011 Jul 25

The New England journal of medicine, 2001-08-16

The New England journal of medicine, 2023 Aug 27

Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG, 2014-04-18

Heart rhythm, 2014-07

Circulation journal : official journal of the Japanese Circulation Society, 2019 Oct 09

The New England journal of medicine, 2023 Aug 27

JACC. Clinical electrophysiology, 2021 Feb 24

Journal of the American Heart Association, 2024 Jan 19

Perfusion, 2021 Jul 28

Current problems in cardiology, 2022 Sep 26

Circulation. Cardiovascular imaging, 2018-03

Circulation, 2023 Aug 27

The New England journal of medicine, 2020 Mar 28

European heart journal, 2023 Jun 09

The New England journal of medicine, 2022 Aug 27

Lupus, 2018 Oct 05

The New England journal of medicine, 2001-11-15

International journal of cardiology, 2023 Aug 01

Lancet (London, England), 2023 Mar 06

The New England journal of medicine, 2023 Nov 11

Circulation. Heart failure, 2021 Dec 20

The New England journal of medicine, 2023 Aug 25

HeartRhythm case reports, 2016-09

Circulation, 2023 Nov 13

Circulation, 2023 Nov 11

Circulation. Cardiovascular quality and outcomes, 2023 Nov 06

American heart journal, 2017 Apr 24

The New England journal of medicine, 2023 Nov 11

American heart journal, 2023 Mar 25

JAMA, 2023 Nov 11

Arrhythmia & electrophysiology review, 2020 Dec

Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2020 Sep 09

Circulation research, 2019 Feb

Journal of the American College of Cardiology, 2020 Aug 11

Lancet (London, England), 2018 Nov 11

Journal of the American Heart Association, 2021 Sep 06

The New England journal of medicine, 2023 Aug 25

Journal of the American College of Cardiology, 1998-07

JACC. Heart failure, 2020 Feb 05

Medwave, 2015 Aug 27

Clinical cardiology, 2023 Jun 20

American journal of physiology. Renal physiology, 2021 May 10

The British journal of cardiology, 2022 Jul 19

Journal of clinical lipidology, 2020 Jan 02

Circulation, 2016-09-06

Circulation, 2023 Mar 16

Journal of the American College of Cardiology, 2022 May 03

Clinical cardiology, 2020 Feb 19

PloS one, 2023 Nov 16

The New England journal of medicine, 1991-03-21

Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2022 Apr 02

Journal of clinical medicine, 2021 Apr 02