Cardiology
Expert discussions on heart failure, arrhythmias, interventional procedures, and cardiovascular risk management.
Recent Discussions
What is a reasonable way to treat statin-induced myalgia and what statin substitute would you consider using in the event the myalgia is not resolved?
Qunol co administration Vytorin - lower doses PCSK9
How do you advise patients with paroxysmal atrial fibrillation regarding their caffeine consumption, given that a randomized clinical trial found no association between caffeine intake and the triggering of AF episodes?
There is no data to support that limited caffeine consumption should not be forced upon patients for AF prevention because it does not cause AF. Then again, there are patients who are sensitive to it and they should avoid it. I think patients are told to stop it because we want to blame something fo...
Which factors would prompt empirical lead extraction in bacteremic patients without TEE evidence of lead vegetation?
My point of view is to have a very low threshold to extract a device where infection is likely. The presence or absence of lead vegetation may be a bit misleading as lead thrombi are not uncommon. I think the presence of a thrombus may make us feel more resolute in the removal plan though this may b...
What is the right approach in terms of GDMT and device consideration for patients with intermittent LBBB (QRS duration exceeding 150ms) and HFrEF?
I would not consider an intermittent left bundle as criteria for BiV pacing. I would actually not consider it in my assessment of heart failure gdmt or device therapy in isolation, whatsoever.
How frequently and when should lipoprotein A levels be monitored?
Lp(a) levels are fairly stable throughout a person's life, which is why the Europeans recommend checking Lp(a) in everyone at least once. Some conditions can increase the level like CKD and hypothyroidism; it’s also an acute phase reactant. Menopause can increase it as well, so one might want to rec...
Given that there are a fair number of myocarditis cases without a troponin elevation, how do you clinically approach the diagnosis of myocarditis?
If clinical suspicion for myocarditis is not based on elevated troponin there needs to be some objective evidence for it. These would be CRP/sed rate/cardiac MR/biopsy. Unlikely to pursue the last step if the first three are all normal.
How do you decide when to refer patients with obstructive hypertrophic cardiomyopathy for alcohol septal ablation versus septal myectomy?
If a patient with obstructive HCM remains severely symptomatic despite being on maximal standard-of-care medical therapy, (beta blockers, non-dihydropyridine calcium channel blockers, addition of disopyramide for combination therapy, or a cardiac myosin inhibitor if appropriate), septal reduction th...
What are your outpatient surveillance strategies (biomarkers, imaging, symptoms) to monitor response to treatment for ATTR amyloidosis with cardiac involvement?
I continue it indefinitely. Limited survival data shows a beneficial effect for at least 5 years with survival on the drug of 55% compared to 37% on placebo.Elliot et al., PMID 34923848However, if patients deteriorate dramatically on therapy and are class IV NYHA, I discuss with patients and family ...
How do you re-stratify patients with a primary prevention ICD in need of a generator change if their LVEF has improved to >40% and they have not previously required any device therapies?
This is an important question on which there remains a lack of consensus. We had tried to address this through an observational study which was published a few years back:(Appropriateness of primary prevention implantable cardioverter-defibrillators at the time of generator replacement: are indicati...
How do you manage patients blood pressures while on anti-angiogenic TKIs?
Advise patients to take BP daily, and inform us if the BP is high.