Hepatology

Medical Oncology

Questions discussed in this category

Should a patient who requires definitive treatment for prostate cancer as a pre-transplant requirement be strictly required to complete their course prior to transplant/initiation of immunosuppression?

Patient is undergoing RT and has already started on a GnRH antagonist. If so, how long after their last fraction would be an appropriate wait time?

1 Answer available

How do you manage anticoagulation/antiplatelet therapies with strong indications for uninterrupted therapy in setting of urgent procedures?

For example, anticoagulation for recent, significant PE or dual antiplatelet therapy for recent MI, but requiring urgent procedures such as biopsy of ...

3 Answers available

Can tacrolimus in a transplant patient be used during radiation and concurrent chemoradiation?

Does your practice differ depending on the disease site?

1 Answer available

Would you recommend radiation or chemoradiation in a patient with cholangiocarcinoma s/p surgery and adjuvant treatment with single hepatic metastasis 3 years later?

Patient with extrahepatic cholangiocarcinoma s/p Whipple in 2021 with negative margins and no positive nodes followed by adjuvant chemo with subsequen...

2 Answers available

When treating with SBRT and immunotherapy for unresectable HCC, how do you sequence the treatment?

Data are scattered, with some starting concurrent and some starting after SBRT to optimize the priming of the immune system with RT.

1 Answer available

What parameters would you use to monitor and interpret iron levels in a hemochromatosis patient where ferritin is unreliable due to underlying chronic inflammation?

How would your recommendation change if the patient has H63 homozygous mutation?

2 Answers available

Would you ever consider using durvalumab/tremelimumab in second line after progression on atezolizumab and bevacizumab in advanced HCC?

3 Answers available

How do you manage oxaliplatin-induced splenomegaly?

1 Answer available

What is your standard diagnostic workup to confirm GVHD in a patient post-BMT with skin rash and jaundice?

2 Answers available

How do you approach restarting immunotherapy in a patient with metastatic melanoma who previously developed immune-mediated hepatitis (Grade 3), with liver enzymes now back to baseline levels?

Given the improvement in liver function, what factors should be considered before reinitiating immunotherapy?"

4 Answers available

Papers discussed in this category

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2024 Mar 19

Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update.

Hepatology (Baltimore, Md.), 2023 May 22

AASLD Practice Guidance on prevention, diagnosis, and treatment of hepatocellular carcinoma.

Hepatology research : the official journal of the Japan Society of Hepatology, 2025 Jan 15

Evaluating two rechallenge strategies of immune checkpoint inhibitors: Durvalumab plus tremelimumab in advanced hepatocellular carcinoma.

Investigational new drugs, 2024 Aug 30

Treatment response to durvalumab plus tremelimumab after progression with previous immune checkpoint inhibitor in unresectable hepatocellular carcinoma.

Radiother Oncol, 2017 May

Analysis of repeated proton beam therapy for patients with hepatocellular carcinoma.

Cancer chemotherapy and pharmacology, 2019 Aug 23

Clinical difference between discontinuation and retreatment with nivolumab after immune-related adverse events in patients with lung cancer.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010-05-20

Oxaliplatin-mediated increase in spleen size as a biomarker for the development of hepatic sinusoidal injury.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2020 Oct 23

Pretransplant solid organ malignancy and organ transplant candidacy: A consensus expert opinion statement.

Hepatology

Medical Oncology

Questions discussed in this category

Papers discussed in this category

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