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Physician discussions on inpatient care, transitions of care, diagnostic reasoning, and hospital-based protocols.

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How do you decide the right time for MitraClip intervention in patients with symptomatic heart failure and severe mitral regurgitation who are on maximally tolerated GDMT?

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Cardiology · West Virginia University School of Medicine

When evaluating these patients, it is always important to consider a multidisciplinary approach inclusive of general cardiologists, imaging experts for MR quantification, and most importantly, heart failure and electrophysiology colleagues. I ensure that the patient is seen by our HF colleagues to t...

Which class(es) of antihypertensives do you recommend for first-line therapy for hypertension in severe aortic stenosis?

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Cardiology · Heart And Sleep Clinics Of America

Most beneficial data on ACE inhibitors.B blockers are to be avoided if associated AR but prior apparent contradiction is no longer valid and some benefit in outcomes based on their effects. Exact Aortic Stenosis substrate and comorbidities to determine which drugs to benefit. ARB's role is probably ...

What treatment would you offer a patient with extensive lymphangioma circumscriptum intermittently covering the entire abdomen?

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Dermatology · Emory University School of Medicine

I would consider sirolimus (rapamycin) to shrink the lesion to a size that could be surgically excised.

What is your approach to DVT prophylaxis in patients who require IVIG but are at increased risk for thrombotic events?

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Neurology · University of Minnesota

I am unaware of any published data to guide the decision-making for this topic. Empirically, I recommend low-dose aspirin in patients >50 who have to get long-term IVIG especially if there are a lot of underlying risk factors for thrombosis like diabetes, immobility, etc. Again, this is not an evide...

What would be your approach to percutaneous intervention for acute plaque rupture and cardiogenic shock for a patient with cirrhosis and severe thrombocytopenia?

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Cardiology · Mount Sinai Heart

Thrombocytopenia is not an absolute contraindication to indicated percutaneous coronary intervention (PCI) and the antiplatelet therapy which it obligates. In a scenario such as this one -- cardiogenic shock complicating an acute myocardial infarction -- PCI is indicated as a life-saving procedure. ...

Do you routinely obtain a CXR or CT after identifying an etiology for dyspnea on POCUS?

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Pulmonology · Grady Memorial Hospital

Sometimes, it depends on the patient. I usually do a POCUS in a patient with dyspnea or respiratory failure. If I think there is an ILD or another disorder causing dyspnea, then I would get a CT.

Are there any varying treatment considerations to make when managing patients with carbonate apatite versus hydroxyapatite kidney stones?

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Nephrology · Mayo Clinic

Both of these stone types require a relatively alkaline urine to crystallize. Not surprisingly, they are often found in combination within the same stone. My diagnostic and treatment considerations do not depend on which mineral composition predominates. Stephen B Erickson, MD

How do you utilize cytokine panels in your clinical practice?

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Rheumatology · Massachusetts General Hospital

It's become easier to order cytokine panels that get processed locally in my hospital. However, I think we're still far from knowing how to interpret these or make clinical changes as a result. While it's tempting to think, "If TNF is elevated, I will give the patient a TNF inhibitor, which will mak...

What additional treatment strategies would you recommend for a patient with a Mycobacterium chelonae and Mycobacterium abscessus infection following bilateral prophylactic mastectomies and implant insertion, who has undergone multiple surgeries and an extended course of IV antibiotics selected based on sensitivities?

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Infectious Disease · Infectious Disease Consultants of South Broward

I assume the implants have been removed. I have had no success trying to treat with retention of the implants (because the patients all want a trial of antibiotics first at the suggestion of the surgeon). If the implants are out, all you can do is continue long courses of antibiotics based on sensit...

What 24 hr urine calcium cut off value do you use for recommending parathyroidectomy in patients with asymptomatic hyperparathyroidism?

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Endocrinology · Duke University Hospital

I use 5.0 mg/kg as a cut point.