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Physician discussions on inpatient care, transitions of care, diagnostic reasoning, and hospital-based protocols.

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How do you approach the choice of basal-bolus insulin vs correctional insulin alone to manage hyperglycemia in a hospitalized older adult with type 2 diabetes and significant frailty?

2 Answers

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Geriatric Medicine · Brown University

Frail older adults with type 2 diabetes, compared to their less-frail counterparts, may have less predictable oral intake, and you may have more difficulty obtaining an accurate medication reconciliation. You may need to review facility records or speak to multiple collateral historians to find out ...

How do you approach the choice of basal-bolus insulin vs correctional insulin alone to manage hyperglycemia in a hospitalized older adult with type 2 diabetes and significant frailty?

2 Answers

Mednet Member
Mednet Member
Geriatric Medicine · Brown University

Frail older adults with type 2 diabetes, compared to their less-frail counterparts, may have less predictable oral intake, and you may have more difficulty obtaining an accurate medication reconciliation. You may need to review facility records or speak to multiple collateral historians to find out ...

Would you consider anti-fibrinolytics for heavy menses in patients with a history of VTE?

1 Answers

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Hematology · University of Pittsburgh

A recent review article provided reassuring evidence about the combined use of antifibrinolytics and estrogen in women with heavy menstrual bleeding (Meschino et al., PMID 40680937); however, it did not specifically provide data in women with a prior history of VTE. In this case, I would first ensur...

How would you counsel a woman with a strong family history of thrombosis about oral contraceptives?

2 Answers

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Hematology · Mayo Clinic

This can be a complex question for which there are likely no specific data or guidelines upon which to base a recommendation. ASH has published guidelines on thrombophilia testing in VTE (Middeldorp et al., PMID 37195076). They specifically recommend against testing prior to COC prescription. The ra...

In older adults with mild cognitive impairment, do you ever prescribe cholinesterase inhibitors and/or memantine?

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5 Answers

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Geriatric Medicine · Wake Forest University School of Medicine

This is a great question, and of course, "do you ever" will get you in trouble every time! Let me start by saying that, in general, I do not prescribe these drugs for MCI. Cholinesterase inhibitors are clearly indicated for the mild-moderate stage of some kinds of dementia (some people would include...

Do you routinely prescribe dry powdered inhalers over metered dose inhalers for the purpose of addressing carbon emissions?

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2 Answers

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Hospital Medicine · University of Vermont Medical Center

Appreciate this question because we often forget just how inextricable the link is between human health and climate health. More specifically, carbon emissions from inhalers worsen the respiratory conditions they are intended to treat. Inhaler prescriptions filled by CMS beneficiaries in 2022 were e...

Do you have a preference between an ACEI and ARB when initiating therapy for a patient with diabetic kidney disease, albuminuria, and hypertension?

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7 Answers

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Nephrology · Rush Medical College

Why would you use an ACEi over an ARB these days? Cough is a LOT more common than stated. I see patients all the time who have a ticket, an annoyance that goes away on an ARB. Also, I don't see a $ argument, nor am I aware that ACEi have even been shown to be superior to ARB for reno protection. Als...

What are some practical tips in distinguishing between metabolic bone disease due to chronic kidney disease and osteoporosis?

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1 Answers

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Nephrology · U Chicago

The biggest difference between osteoporosis and CKD-MBD has to do with the underlying bone mineral laboratories. Generally, with osteoporosis, bone chemistries are relatively normal; there may be a decrease in Vit D. However, with CKD-MBD, there is usually an increase in PTH, potentially abnormaliti...

Do you use DOAC in patients with mild or moderate rheumatic mitral stenosis?

4 Answers

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Cardiology · Lankenau Heart Group

Although using DOACs in this population may be safe, these patients were excluded from the large DOAC trials. In addition, MS progresses, so what may be moderate disease today will progress rapidly in some patients. Thus, if anticoagulation is necessary and a VKA is a major issue for the patient, a ...

How do you counsel patients on the risks and benefits of antidepressant use during pregnancy?

2 Answers

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Psychiatry · Oregon Health Sciences University

I always frame the decision as being between the risks and benefits of the medication vs. the underlying condition. We are always aiming for the "minimum effective dose" but "effective" is just as important as "minimum." Medications are, of course, not the only way to treat psychiatric illness and a...