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Hospital Medicine

Hospital Medicine

Physician discussions on inpatient care, transitions of care, diagnostic reasoning, and hospital-based protocols.

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When telemetry or ECG shows a newly prolonged QTc (e.g., >500 ms) in an otherwise stable hospitalized patient, how aggressively do you modify medications, electrolytes, or monitoring?

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1 Answers

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Hospital Medicine · Yale School of Medicine/Yale-New Haven Hospital

A newly prolonged QT can be easy to overlook amid the complexity of inpatient hospitalization, and when identified, I generally add it to the problem list so it remains visible during the admission and in future care. Although prolonged QT is associated with torsades de pointes, sudden cardiac death...

How do you think about using contraction alkalosis as a mark of achieving goal diuresis?

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Hospital Medicine · Yale School of Medicine/Yale-New Haven Hospital

Thank you for your insightful question. Residual congestion at discharge for patients treated for decompensated heart failure is associated with increased rates of readmission and mortality. While I do occasionally use the development of metabolic alkalosis as a marker of decongestion, a review of t...

How have the new USDA Dietary Guidelines which seem to promote several sources of saturated fat (i.e., full fat dairy products, butter, red meat) changed how you approach dietary advice with your patients?

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Primary Care · Albert Einstein College of Medicine

It has not changed my recommendations at all. I still recommend a whole-food, plant-predominant eating pattern, which has been shown to improve health across a variety of chronic conditions and often can be used to treat, prevent, and sometimes reverse chronic disease. However, the new guidelines do...

How do you manage severe Raynaud's phenomenon with ulceration in scleroderma patients that is refractory to oral agents (CCBs, PDEis, ARBs, and ERAs)?

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Rheumatology · Johns Hopkins University

Difficult question. First, I would make sure that the ulcers you are trying to treat are really ischemic in etiology. These would typically be ulcers that are on the fingertips in association with significant Raynaud's. Other etiology for ulcers would be trauma/skin fragility (over PIP joints most c...

How does premorbid dementia affect your decision to offer acute stroke intervention?

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Neurology · Vanderbilt University Medical Center

Patients with dementia can still benefit from endovascular thrombectomy. Of course, they can at best be restored to their previous level of function, including their cognitive deficits. If the quality of life of the patient is still satisfactory, however, this treatment is justified. This position i...

What advice do you have for new hospitalists attending on teaching services for the first time?

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Hospital Medicine · Yale School of Medicine/Yale-New Haven Hospital

My advice is to focus less on being the "expert" and more on creating the conditions for learning. Medical education has changed considerably over the past decade. We now recognize that the most effective teaching attendings are not simply those with the greatest fund of knowledge, but those who fos...

How do you counsel patients who develop DVT or atrial fibrillation requiring anticoagulation when being treated with lecanemab or donanemab?

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Neurology · HCA Houston Healthcare

I believe until further data/studies are available, I would prefer not to use anticoagulation (at least long term) without comprehensive discussion among other treating physicians depending on the indication. The lecanemab appropriate use recommendations (Cummings et al., PMID 37357276) recommend ag...

How do you approach a patient on anti-TNF with positive Quantiferon (previously negative) with negative chest x-ray and no symptoms?

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11 Answers

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Rheumatology · University of Cincinnati

Prior to routine screening for latent TB for patients receiving or about to receive TNF inhibitor therapy, there were reports of miliary TB developing after initiation of TNF inhibitors. Therefore, one cannot say that a negative chest x-ray and no symptoms means the patient is not at risk for develo...

How do you counsel patients on peritoneal dialysis regarding the safety of engaging in aerobic and resistance exercises, considering the risk of developing abdominal wall complications?

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Nephrology · UCHealth University of Colorado Hospital (UCH)

The effect of exercise on intra-abdominal pressure (IAP) while on PD was examined decades ago by Twardowski et al., PMID 3774076. They found that walking, jogging, or using an exercycle resulted in only modest increases in IAP, while jumping or straining (e.g. weight- lifting) resulted in more marke...

Would you stop an ACE inhibitor/ARB or instead initiate a potassium binder to manage hyperkalemia in a patient with proteinuric CKD stage 5 who is on an ACEi/ARB?

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Nephrology · Penn Medicine Cherry Hill

This depends on where in CKD 5 the patient is, to some extent. Would also make sure to modify diet if possible and make sure on an appropriate dose of a loop diuretic. If very close to starting dialysis or getting a txp, I might reduce dose or stop, especially if a K-binder is expensive for the pati...