Obstetrics & Gynecology

Hemostasis/Thrombosis

Questions discussed in this category

What is your approach to pregnant patients with type 2B von Willebrand disease, particularly when thrombocytopenia is already present?

2 Answers available

What guides your choice between prophylactic, intermediate, and full therapeutic dosing of enoxaparin in a woman with APLS and prior fetal loss with no hx of thromboembolic disease?

2 Answers available

For patients with a history of pregnancy loss, do you evaluate for PAI-1 polymorphisms as part of a thrombophilia workup?

If positive, do you anticoagulate for subsequent pregnancies?

1 Answer available

How often do you check weight and adjust anticoagulation dosing in pregnancy?

1 Answer available

Papers discussed in this category

Trials, 2015-05-07

ALIFE2 study: low-molecular-weight heparin for women with recurrent miscarriage and inherited thrombophilia--study protocol for a randomized controlled trial.

Annals of the rheumatic diseases, 2019-10

EULAR recommendations for the management of antiphospholipid syndrome in adults.

BMJ (Clinical research ed.), 1997 Jan 25

Randomised controlled trial of aspirin and aspirin plus heparin in pregnant women with recurrent miscarriage associated with phospholipid antibodies (or antiphospholipid antibodies).

Arthritis Care Res (Hoboken), 2020 Apr

2020 American College of Rheumatology Guideline for the Management of Reproductive Health in Rheumatic and Musculoskeletal Diseases.

Blood advances, 2018-11-27

American Society of Hematology 2018 guidelines for management of venous thromboembolism: venous thromboembolism in the context of pregnancy.

Lancet (London, England), 2022 Oct 28

Intermediate-dose versus low-dose low-molecular-weight heparin in pregnant and post-partum women with a history of venous thromboembolism (Highlow study): an open-label, multicentre, randomised, controlled trial.

Blood, 2018-03-22

How I treat type 2B von Willebrand disease.

Blood, 2008 Sep 19

Clinical and molecular predictors of thrombocytopenia and risk of bleeding in patients with von Willebrand disease type 2B: a cohort study of 67 patients.

Blood, 2018 May 17

Kruse-Jarres R, Johnsen JM. How I treat type 2B von Willebrand disease. . 2018;131(12):1292-1300.

Journal of thrombosis and haemostasis : JTH, 2022 Dec 22

Challenges in the management of women with type 2B von Willebrand disease during pregnancy and the postpartum period: evidence from literature and data from an international registry and physicians' survey-communication from the Scientific and Standardization Committees of the International Society on Thrombosis and Haemostasis.

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