Ophthalmology
Expert insights on ocular conditions, surgical techniques, retinal disease, and vision-related management.
Recent Discussions
What factors guide the decision to treat with ROP laser treatment versus a repeat anti-VEGF injection in a child who has previously received anti-VEGF therapy for retinopathy of prematurity (ROP)?
In patients who have a recurrence of stage 3 neovascular ROP following anti-VEGF injection, I will typically perform laser unless the patient is systemically unstable and cannot tolerate sedation or anesthesia, or unless the patient still has very posterior disease (zone 1 or posterior zone 2). In p...
Has the CONDOR trial changed your first-line approach to treatment-naive proliferative diabetic retinopathy in a patient with good visual acuity who is able to attend regular follow-up visits?
No. In the US, we stopped using brolucizumab (Beovu) because of the risk of retinal vasculitis. So I don’t even think I can get that medicine anymore. For those who don’t know about it, CONDOR was a trial that studied the use of Beovu vs. PRP (panretinal photocoagulation) for proliferative diabetic ...
When would you offer neoadjuvant immunotherapy prior to Mohs surgery in a locally advanced squamous cell carcinoma for which clearance may require enucleation?
I would flip this question around and answer that radiotherapy is often a terrific option around the eyes, and it should always be considered in this area, especially when a radical surgical procedure is being entertained. Between en face therapy with a shield (superficial, electrons) and IMRT/VMAT,...
How do you approach the use of Cequa in eyes with severe corneal thinning from a prior, healed corneal ulcer?
The use of Cequa or other cyclosporins has not been associated with an increased risk of thinning. Cequa prescribing information lists no contraindications and reports instillation site pain and conjunctival hyperemia as the main adverse reactions. Corneal thinning, impaired healing, and perforation...
How do you approach a patient who has anterior uveitis and is referred for evaluation of ocular TB with a positive Quantiferon gold (as part of their workup) in countries with low TB incidence?
It is a frustrating problem and is expected to increase without solid evidence. Until then, management should involve an interdisciplinary collaborative approach and a shared decision-making process.I see the following issues. I feel ophthalmologists follow the diagnostic criteria for TB uveitis us...
For patients with Light Adjustable Lenses, what has been your approach regarding YAG capsulotomy timing?
It is best to avoid performing a YAG capsulotomy before or during the light-adjustment period unless the posterior capsule opacification (PCO) is visually significant and functionally limiting. Although the YAG laser itself is safe and effective regardless of its timing relative to lens lock-in, sev...
Are there clinical situations where you would advise removal of the LASIK flap and how do you determine if it is clinically necessary?
I had a patient who had recurrent and persistent epi ingrowth into the flap interface, and eventually all of that epi ingrowth caused the flap to sectorally melt. I decided to amputate the flap and let the interface just grow over with epithelium. Surprisingly, the patient did quite well and, once h...
What pre-operative features in pseudoexfoliation patients do you feel correlate with intra-op zonulopathy?
This is an excellent question. Several factors play a role in the extent of zonulopathy that one may expect during pseudoexfoliation cases. A history of zonulopathy in the other eye or other factors that could contribute (trauma, falls, prior surgeries like retina procedures) would be one thing to l...
How often and in what way do you monitor patients who are receiving teprotumumab (Tepezza) for thyroid eye disease?
A week or two after completion unless having an issue.
What is your approach to offering PRK for 1 diopter of myopia in patients over 45 with a corneal thickness of 450 microns and no keratoconus?
I am not sure why you would treat this patient? One diopter of myopia over 45 years old. The patient probably has pretty good reading and distance vision without glasses. What is the patient’s visual goal? They want 20/20 distance without correction and now lose all ability to read?