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Physician perspectives on preventive care, chronic disease management, and evidence-based primary care practice.

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When do you recommend patients get vaccinations with respect to their RT course?

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Radiation Oncology · University of Pennsylvania

I agree with @Dr. First Last's reply, and find that some patients are under the impression they are immunocompromised during radiation therapy and thus should avoid vaccines, when in fact the opposite is true. The skepticism behind the science of vaccination also can lead to avoidance, and so I try ...

How long would you recommend that a patient continues guselkumab prior to deciding that the therapy is not effective?

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4 Answers

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Rheumatology · Leiden University Medical Center

Many trials have a placebo-controlled period of 12-24 weeks. Thereafter, all patients receive active treatment. Even if the original treatment allocation remains unknown to the patient and doctor, they know that from that moment on, everyone receives active treatment. This will have an influence on ...

How do you present the trade off between a small chance of a sustained response for a new drug at the expense of potential worsening quality of life?

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Medical Oncology · Memorial Sloan Kettering Cancer Center

Since we now have an increasing number of treatments at our disposal, this becomes an ever more frequent conversation in oncology. This question gets at several Shared Decision Making (SDM) model steps. Usually in this scenario, there are not routine standard of care options and highlighting the pat...

Is your approach to managing immune related adverse events altered at all in light of COVID-19?

2 Answers

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Medical Oncology · Albert Einstein College of Medicine at Montefiore Medical Center

First of all, I wish to thank @Dr. First Last from Johns Hopkins/Sibley for his advice addressing this critical topic.We are all witnessing a rapidly evolving crisis that none of us have been prepared for and it is the right thing to quickly consider as best as we can how the COVID-19 pandemic shoul...

Would you use the pneumococcal conjugate-21 vaccine (Capvaxive) instead of the conjugate-20 (Prevnar-20) for routine vaccinations in immunosuppressed patients?

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Infectious Disease · Harbor - UCLA Medical Center

PCV-21 was recently approved by the FDA and supported by ACIP. At this early stage (August 2024), CDC has not finalized guidance on PCV-21, so we do not know how the vaccine schedule will be changed. An important distinction is that PCV-21 covers different serotypes of pneumococcus, as outlined in t...

What measures should we take regarding routine follow-up visits for well patients in surveillance during the coronavirus pandemic?

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Radiation Oncology · Meadowview Regional Medical Center

3-6 months.

Do you recommend allopurinol desensitization in gout patients who develop a rash on allopurinol therapy?

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Rheumatology · National institues of Health

I don't recommend desensitization for allopurinol-allergic patients. There was a time when this made sense due to the lack of a viable alternative therapy. The process is cumbersome in a private practice setting and not as simple as providing the patient with a prescription for febuxostat.Febuxostat...

Are there scenarios that new visits/consults with patients can be done virtually amidst the COVID-19 outbreak?

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6 Answers

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Medical Oncology · Mayo Clinic Rochester

Starting 3/16, we began offering lower-complexity / lower-risk patients the option of having a Tele-medicine consult vs re-scheduling to a later date. This offer has been extended broadly to all new consults at our facility when the provider indicates that s/he can extend comparable service virtuall...

What are best practices for taking care of lung cancer patients during the COVID-19 pandemic?

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Medical Oncology · Indiana University

This is a great question, and as always there is no one size fits all. For patients on active treatment for lung cancer such as chemoimmunotherapy, I continue to stress the importance of hand washing, social distancing, and to work on reducing wait times in the waiting room to limit exposure, etc. I...

What is your clinical approach to deprescribing vs continuing low-dose aspirin used for primary prevention in older adults who are already taking this medication?

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Cardiology · Methodist Cardiology Clinic Of San Antonio Westover Hills

I generally continue a low-dose aspirin in patients at higher risk (e.g., diabetes, CKD, strong family history) who would be at risk for a significant reduction in quality of life were s/he to have a cardiac/vascular/cerebrovascular event, provided there is no history of significant anemia (transfus...