Von Willebrand

Questions discussed in this category

What is your preferred treatment agent for type 1 von Willebrand patients needing minor procedures if they have a history of severe hyponatremia with DDAVP?

Hyponatremia occurred despite fluid restriction. Do you favor factor replacement? Or do you continue to try DDAVP and add urea +/- salt tablets, in a...

3 Answers available

How do you approach delivery planning in patients with T1 vWD?

Do you routinely recommend a C-section over vaginal delivery? Induced vs spontaneous? If a C-section is needed, do you prefer general anesthesia over...

2 Answers available

What is the best way to prepare children with von Willebrand disease for tonsillectomy to reduce the risk of post-operative hemorrhage?

1 Answer available

Would you consider IV thrombolytics in patients with acute ischemic stroke, with or without a large vessel occlusion, if they have a history of von Willebrand disease (VWD), regardless of its type?

Would you ask for a hematologist to weigh in on this emergently?

1 Answer available

In a patient with type I von Willebrand disease who is pregnant and at increased risk for preeclampsia, would you recommend treatment with aspirin?

Risk factors for preeclampsia include advanced maternal age and twin gestation. Would your thinking differ if their bleeding history is limited to ea...

1 Answer available

For von Willebrand type 2B, do you expect a decline in platelet count over time as vWF increases with age?

1 Answer available

Is there any benefit to using desmopressin over vWF replacement therapy for vWD?

If not, has your practice changed to use vWF replacement therapy more routinely for perioperative or acute bleeding management? Do you still perform D...

1 Answer available

How do you manage mild Type 1 von Willebrand disease undergoing wisdom teeth removal?

Antifibrinolytic therapy alone +/- DDAVP?

1 Answer available

How do you interpret a low VWF activity/antigen ratio, when both activity and antigen levels are above 50%?

E.g. Normal F8, VWF activity ~50%, VWF antigen ~100%, ratio 0.5 sent in a patient with positive bleeding history Is there any clinical significance t...

1 Answer available

Do you screen for VWD in all women with menorrhagia severe enough to cause iron deficiency anemia?

3 Answers available

How would you manage anti-platelet therapy in patients presenting with ischemic stroke and have a history of von Willebrand disease?

1 Answer available

What is the optimal management of a patient needing surgical clearance for a knee replacement with VWF Ag and factor VIII between 40-50 and no bleeding history?

1 Answer available

In a patient with a bleeding disorder, how would one approach anticoagulation during active COVID infection?

Bleeding disorder such as vWD

1 Answer available

How would you manage a patient with acquired von Willebrand disease who requires DAPT for arterial disease?

1 Answer available