Do you add elafibranor or seladelpar to UDCA within the first year of treatment in a patient with primary biliary cholangitis who has an inadequate alkaline phosphatase response but no symptoms of pruritus?

Community PollStarted

All patient factors being equal, is elafibranor or seladelpar your "go-to" second line agent in the management of PBC?

3 physicians have voted

Join Mednetto vote and see how they answered.

1 Answer

Mednet Member

Hepatology · UChicago Medicine

Answered on

I usually will wait for a year with the first line agent, ursodiol, if it is well-tolerated and there are no symptoms, before declaring inadequate alkaline phosphatase response and moving on to a second line agent for primary biliary cholangitis.

Join for free or sign in to see the full answer