Do you add fludrocortisone to hydrocortisone when starting stress dose steroids in a patient with septic shock?

Topics: Pulmonology • Critical Care • Shock

Though there is data to support using both hydrocortisone and fludrocortisone, it seems to be used rarely in clinical practice.

A review published 12/29/2023 article explores this question (PMID: 38156911)

Answer from: at Academic Institution

In septic shock, vasoplegia is mostly believed to be related to widespread inflammation that giving hydrocortisone is supposed to address, and current guideline suggests hydrocortisone only is sufficient. However, it makes sense to add fludrocortisone since most of these patients present with undefi...

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at Cedars-Sinai Medical Center
Thanks for your response. It interests me that tho...

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