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Do you add trastuzumab to adjuvant chemotherapy for patients with Her2+ stage I-II high grade serous uterine cancer following surgical staging?

Or would you reserve its use to stage III-IV or recurrent disease (as in Fader et al., PMID 29584549)?
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In what circumstances do you administer trastuzumab for uterine serous carcinoma?

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1 Answer
Mednet Member
Mednet MemberInvited Expert
Gynecologic Oncology · Center of Hope
Answered on

No, I don’t routinely add trastuzumab to adjuvant chemotherapy for early stage Her2+ serous endometrial cancer patients. There are no data supporting its use in this manner. My recommendation is to offer her treatment on GY026, a study enrolling both early and late-stage serous endometrial cancer pa...

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