Do you approach the diagnosis and treatment of HIT patients differently in the outpatient setting or in a resource-limited community setting?
For example, for outpatients or resource-limited settings with a moderate probability 4-T score (but low clinical suspicion), would you ever consider waiting for HIT testing before changing to nonheparinoid agent. Or would you switch a patient to immediately (to a DOAC or fondaparinux) given the risk?
Answer from: Medical Oncologist at Academic Institution
The concern for heparin induced thrombocytopenia is a complex problem. If the patient has HIT by 4T score and thrombosis, then admission to the hospital for initial management including direct thrombin inhibitor is the correct path awaiting confirmation by ELISA and platelet release assay. If negati...
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