Is there a role for DOAC use for patients with unprovoked PE, that have had recent sleeve gastrectomy with duodenal bypass?

Alterations in the gastrointestinal (GI) tract following bariatric surgery, as well as altered or reduced oral intake, have the potential to impair the absorption of both DOACs and VKAs in the acute setting. DOACs are absorbed in the upper GI tract, which is altered by the most common bariatric surgical procedures including Roux-en-Y gastric bypass (RYGB), sleeve gastrectomy, and duodenal switch. The anticipated effect of each of these surgeries on luminal absorption depends on the specific type...