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Do you avoid potassium citrate in patients with recurrent nephrolithiasis and hypocitraturia if they also take antihistamine medications?

2 Answers
Mednet Member
Mednet Member
Nephrology · University of Chicago Medicine

I know of no data showing effects of antihistamine meds on urine citrate or on the effects of potassium citrate on urine citrate. I made a Perplexity search which also found no evidence - this is not a topic I have personally researched because I have never encountered clinical issues about it. So -...

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Mednet Member
Mednet Member
Nephrology · WMCHealth

Acetazolamide use can make using citrate tricky, and need to watch urine pH and monitor for the development of calcium phosphate stones. The use of citrate can be a double-edged sword in the setting of Acetazolamide use.

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