Do you consider ADT intensification with enzalutamide or abiraterone in patients receiving adjuvant radiation with ADT?
1
2 AnswersMednet Member
Radiation Oncology · Case Western Reserve University/ University Hospitals Seidman Cancer Center
I agree with Dr. @Dr. First Last.
One thing to note is ~3% of RADICALS, for example, included pT3b and high grade disease, and almost no patients in the ART vs SRT trials had N+ disease. Was largely GS7 and pT3a population and not the very high risk patients that select surgeons choose to operate on....
Mednet Member
Medical Oncology · Duke University School of Medicine
The short answer is no. The long answer is that most men even with high risk prostate cancer are presently treated with early salvage RT +/- ADT rather than adjuvant RT +/- ADT given the results of 3 recent phase 3 trials which demonstrated similar results for early salvage radiation vs adjuvant RT,...