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Do you consider idiopathic pulmonary fibrosis a contraindication to lung SBRT?

There are varying reports in the literature which seem to suggest increased rates of Gr 4-5 pneumonitis in IPF patients. How do you manage these patients in your practice?
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Do you consider idiopathic pulmonary fibrosis a contraindication to lung SBRT?

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2 Answers
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Radiation Oncology · Cleveland Clinic
Answered on

The number of IPF patients treated at our institution has been relatively small, at less than 5%. When they have presented with medically inoperable early lung cancer, we have discussed the risk and benefits of lung SBRT with a focus on lung toxicity that may be more prevalent in this clinical scena...

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Radiation Oncology · University of Louisville
Answered on

I agree with Greg. We have a relatively large IPF population at our institution who happen to be smokers, although still representing 3-5% of lung SBRT patients. Although I have seen severe pneumonitis in this group, it has not precluded this patient population from receiving treatment. Pneumonitis ...

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