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Do you consider MSI testing for mCRPC?

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Mednet Member
Mednet Member
Medical Oncology · Memorial Sloan-Kettering Cancer Center

I agree that data for response to immunotherapy in MMR-deficient (dMMR) prostate cancer is limited, and we estimate the rate of dMMR in prostate cancer to be low, in the 2-3% range. Nonetheless, based on responses in other dMMR tumors, pembrolizumab is now FDA approved for all dMMR/MSI-high unresect...

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Mednet Member
Mednet Member
Medical Oncology · University of Virginia

In contrast to the state of molecularly targeted therapeutics in other solid tumors such as lung cancer and melanoma our current knowledge base in prostate cancer is really just getting started with encouraging early data with regards the frequency and ability to target DNA mismatch repair abnormali...

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Do you consider MSI testing for mCRPC? | Mednet