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Do you consider post-operative radiation therapy for pancreatic neuroendocrine carcinoma?

If so, what clinicopathologic features would indicate consideration of radiation therapy?
2 Answers
Mednet Member
Mednet Member
Radiation Oncology · HistoSonics, Inc.
Answered on

In collaboration with @Dr. First Last, MD, Northwell Health Radiation Oncology Resident

The first and most important point is that there is no clear level I or even prospective evidence to inform the use of radiation therapy for pancreatic neuroendocrine cancers, and it is unlikely that there will b...

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Mednet Member
Mednet MemberInvited Expert
Radiation Oncology · Memorial Sloan-Kettering Cancer Center
Answered on

There is no defined role for adjuvant or neoadjuvant radiation for PNET. There is a lot of evidence that well and mod diff is resistant to radiation and all PNETs have a formidable risk of DM.

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