Topics:
Radiation Oncology • Gastrointestinal Cancers
Do you consider post-operative radiation therapy for pancreatic neuroendocrine carcinoma?
If so, what clinicopathologic features would indicate consideration of radiation therapy?
Answer from: Radiation Oncologist at Community Practice
In collaboration with @Daniel Koffler, MD, Northwell Health Radiation Oncology Resident The first and most important point is that there is no clear level I or even prospective evidence to inform the use of radiation therapy for pancreatic neuroendocrine cancers, and it is unlikely that there w...
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Answer from: Radiation Oncologist at Academic Institution
There is no defined role for adjuvant or neoadjuvant radiation for PNET. There is a lot of evidence that well and mod diff is resistant to radiation and all PNETs have a formidable risk of DM.