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Do you continue daratumumab beyond 24 months in first line treatment of amyloidosis?

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Mednet Member
Mednet Member
Medical Oncology · OhioHealth

While Andromeda only goes to 24 mos, I usually go beyond that: especially in these scenerios

  • patient has smoldering myeloma (instead of MGUS)
  • high risk mutations: t(4:14). rarely do we see TP53
  • Persistent MRD+. I do repeat BMs and MRD assessment at least first 2 years ( thankfully we have not had probl...

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