Do you escalate the dose in adjuvant pancreatic cancer radiation therapy similar to how many are treating locally advanced disease with dose escalation?

A few points to consider about this modern perspective on adjuvant CXRT for pancreatic cancer are:

• A positive margin is one of the least controversial indications for adjuvant CXRT in pancreatic cancer.
• If you get a case to treat, you don't want dose to be the reason for failure.
• 50.4 Gy has been th...

Thanks for the great insights from Dr. @Dr. First Last!

I am wondering if you changed your practice based on the presented RTOG 0848 trial results. There was no interaction with margin status, and it seems that chemoradiation benefit is mostly limited to patients with pN0 disease.

Do you still reco...